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| Product | Description | |
|---|---|---|
| BAY 60-6583 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| BAY 60-6583 | BAY 60-6583 is a potent and high-affinity agonist of adenosine A 2B receptor ( EC 50 = 3 nM) over A1, A2A, and A3 receptors. BAY 60-6583 binds to mouse, rabbit, and dog A2BAR with K i values of 750 nM, 340 nM and 330 nM, respectively. BAY 60-6583 has a cardioprotective effect in a myocardial ischemia model [1] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 910487-58-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103171. |  |
| BAY 60-6583 | BAY 60-6583 is a potent and selective adenosine A2B receptor agonist. BAY 60-6583 shows protective effects against ischemia in both the heart and kidney in animal models. BAY 60-6583 is also a useful therapeutic drug in the treatment of acute lung injury. Group: Biochemicals. Alternative Names: 2- [ [6-Amino-3, 5-dicyano-4- [4- (cyclopropylmethoxy) phenyl] -2-pyridinyl] thio] acetamide; BR 4887. Grades: Highly Purified. CAS No. 910487-58-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C19H17N5O2S. US Biological Life Sciences. |  Worldwide |
| BAY 60-6583 | BAY 60-6583 is a potent and selective adenosine A2B receptor agonist (EC50 = 2.83 nM for murine A2B receptor) displaying selectivity for A2B over A1, A2A and A3 receptors. BAY 60-6583 decreases fMLP-induced superoxide production in neutrophils at low concentrations (1-10 nM) and attenuates infarct size in a mouse model of myocardial ischemia, suggesting that it may be beneficial for the treatment of disorders in the coronary arteries, atherosclerosis and ischemia-reperfusion injury. Synonyms: BAY 60-6583; BAY-60-6583; BAY60-6583. 2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide; BR 4887. Grades: ≥98% by HPLC. CAS No. 910487-58-0. Molecular formula: C19H17N5O2S. Mole weight: 379.44. |  |
| BAY 60-6583-13C2,15N | BAY 60-6583-13C2,15N. Group: Biochemicals. Alternative Names: 2- [ [6-Amino-3, 5-dicyano-4- [4- (cyclopropylmethoxy) phenyl] -2-pyridinyl] thio] acetamide-13C2, 15N; BR 4887-13C2,15N. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1713C2H17N415NO2S, Molecular Weight: 382.41. US Biological Life Sciences. | Worldwide |
| KI-7 | KI-7 is an A2B adenosine receptor positive allosteric modulator. KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC 50 =445.8 nM). KI-7 also potentiates the cAMP accumulation induced by the selective A2B adenosine receptor agonist BAY 60-6583 as well as by adenosine with EC 50 s of 2390 nM and 2550 nM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1489263-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-131032. | |
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