Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| BC-1215 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| BC-1215 | BC-1215 is an inhibitor of F-box protein 3 (FBXO3) with an IC50 of 0.9 μg/mL for IL-1β release. It acts by antagonizing Fbxo3 in TRAF cell signaling and displays a low IC50 in vitro. BC-1215 can be used for inflammation research. Synonyms: N1,N2-bis[[4-(2-pyridinyl)phenyl]methyl]-1,2-ethanediamine. Grades: ≥98%. CAS No. 1507370-20-8. Molecular formula: C26H26N4. Mole weight: 394.51. |  |
| Fbxo3 Inhibitor, BC-1215 (N1,N2-bis(4-(Pyridin-2-yl)benzyl)ethane-1,2-diamine, F Box Only Protein 3 Inhibitor, F Box Protein 3 Inhibitor, BC1215, F Box and Leucine-rich Repeat Protein 2 Activator, Fbxl2 Activator) | A cell-permeable, bis-pyridinyl benzyl ethanamine that disrupts Fbxo3-Fbxl2 interaction and effectively prevents SCF-Fbxo3-catalyzed Fbxl2 ubiquitination, resulting in cellular Fbxl2 upregulation and thereby SCF-Fbxl2-catalyzed TRAFs (TNF Receptor-Associated Factors) ubiquitination. Effectively reduces cellular TRAFs (5 to 127uM) and prevents TRAF-mediated cytokines production from LPS-stimulated human PBMC (25uM). Shown to greatly prevent Cecal Ligation & Puncture-induced plasma cytokine elevation and substantially reduce the severity of lung inflammation post intratracheal P. aeruginosa infection in mice (100ug/mouse; i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?, Primary Target: Fbox3. US Biological Life Sciences. |  Worldwide |
Our database is helping our users find suppliers everyday.
