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Beauvericin is a cyclic depsipeptide isolated from several fungal genera, notably Beauveria and Fusarium, first reported in 1969. Beauvericin exhibits broad antifungal, antibacterial, antiprotozoan and insecticidal activities. At the molecular level, beauvericin has been shown to exhibit ionophoric properties and inhibits acyl- CoA:cholesterol acyltransferase activity. Beauvericin induces apoptosis by elevating intracellular calcium levels. Group: Biochemicals. Grades: Highly Purified. CAS No. 26048-05-5. Pack Sizes: 5mg. US Biological Life Sciences.
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Beauvericin
Beauvericin is a cyclohexapeptide Fusarium toxin with insecticidal, antibacterial, anticancer, antiviral and cytotoxic activities. Beauvericin causes cellular genotoxicity by producing DNA breaks, chromosomal aberrations and micronuclei, and inhibits the PI3K/AKT pathway to induce apoptosis , thereby inhibiting the growth of HCC. In addition, Beauvericin affects immune function by inhibiting lymphocyte proliferation and interfering with the differentiation process of human monocytes into macrophages [1] [2] [3] [4] [5] [6] [7] [8] [9]. Uses: Scientific research. Group: Natural products. CAS No. 26048-05-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N6739.
Beauvericin
Beauvericin is produced by the strain of Streptomyces sp. Ba cyclic depsipeptide isolated from several fungal genera, notably beauveria and fusarium; exhibits broad antifungal, antibacterial, antiprotozoan and insecticidal activities; exhibits ionophoric properties, and inhibits acyl-coa:Cholesterol acyltransferase activity; induces apoptosis by elevating intracellular calcium levels. Synonyms: Cyclo(-D-alpha-hydroxyisovaleryl-N-Me-Phe)3. Grades: >97% by HPLC. CAS No. 26048-05-5. Molecular formula: C45H57N3O9. Mole weight: 783.95.
Beauvericin A
Beauvericin A is a cyclodepsipeptide and derivative of beauvericin originally isolated from B. bassiana that has diverse biological activities. It is active against M. tuberculosis (MIC = 25 μg/ml) and P. falciparum (IC50 = 12 μg/ml). Synonyms: Beauvericin A; 165467-50-5; (3S,6R,9S,12R,15S,18R)-3,9,15-tribenzyl-6-[(2S)-butan-2-yl]-4,10,16-trimethyl-12,18-di(propan-2-yl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone; (3S,6R,9S,12R,15S,18R)-4,10,16-trimethyl-6,12-bis(1-methylethyl)-18-[(1S)-1-methylpropyl]-3,9,15-tris(phenylmethyl)-1,7,13-trioxa-4,10,16-triazacyclooctadecane-2,5,8,11,14,17-hexone; CHEMBL506228; AKOS040754812. Grades: >95% by HPLC. CAS No. 165467-50-5. Molecular formula: C46H59N3O9. Mole weight: 797.97.
(3S,6R)-Lateritin
N-methylated peptide that is structurally equivalent to a monomer of beauvericin. Acyl-CoA:cholesterol acyltransferase inhibitor. Platelet aggregation inhibitor. Antimicrobial. Note: The (3R,6R)-stereoisomer was shown to have anti-cancer and apoptosis inducing activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 65454-13-9. Pack Sizes: 1mg. Molecular Formula: C15H19NO3. US Biological Life Sciences.
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