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| Product | Description | |
|---|---|---|
| Belotecan | Belotecan binds to and inhibits the activity of topoisomerase I, stabilizing the cleavable complex of topoisomerase I-DNA, which inhibits the religation of single-stranded DNA breaks generated by topoisomerase I. Uses: Topoisomerase i inhibitors. Synonyms: Camtobell; CKD602; CKD 602; CKD-602; (4S)-4-Ethyl-4-hydroxy-11-(2-(isopropylamino)ethyl)-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione. CAS No. 256411-32-2. Molecular formula: C25H27N3O4. Mole weight: 433.50. |  |
| Belotecan | Belotecan (CKD-602 free base) is a DNA topoisomerase I inhibitor. Belotecan induces cell apoptosis and cell-cycle arrest. Belotecan is a camptothecin analogue with anti-tumor effects, it can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CKD-602 free base. CAS No. 256411-32-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-13566. |  |
| Belotecan hydrochloride | Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic camptothecin derivative. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CKD-602. CAS No. 213819-48-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13566A. | |
| CKD 602 | CKD-602 is a topoisomerase I inhibitor. It is a synthetic and water-soluble camptothecin derivative which forms stable DNA-topoisomerase complexes during DNA replication and induces cell cycle arrest in the G2/M phase. CKD-602 has a significant effect on intracerebral glioma growth, with animals having significantly smaller tumors than those in the control group. Synonyms: (4S)-4-Ethyl-4-hydroxy-11-[2-[(1-methylethyl)amino]ethyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione phosphate; Belotecan hydrochloride. Grades: ≥98% by HPLC. CAS No. 213819-48-8. Molecular formula: C25H27N3O4·H3PO4. Mole weight: 531.49. | |
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