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Bepotastine is a 2nd generation antihistamine. It is currently marketed in the United States as an eye drop under the brand-name Bepreve, by ISTA Pharmaceuticals. Bepotastine is a histamine H1 receptor antagonist. Bepotastine suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus). The opthalmic solution is FDA approved since Sept 8, 2009 and is under the brand name Bepreve. Synonyms: TAU284; TAU-284; TAU 284; Talion; Bepreve. Grade: ≥98%. CAS No. 125602-71-3. Molecular formula: C21H25ClN2O3. Mole weight: 388.89.
Bepotastine
Bepotastine is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 125602-71-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-I0021.
Bepotastine
Bepotastine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic acid. CAS No. 125602-71-3. Molecular formula: C21H25ClN2O3. Mole weight: 388.89. Catalog: APB125602713.
Bepotastine besilate
Bepotastine besilate is a selective and orally active second-generation histamine H1 receptor antagonist, can suppress the expression of nerve growth factor (NGF). Bepotastine besilate has the potential for allergic rhinitis, allergic conjunctivitis and urticaria/pruritus research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 190786-44-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-A0015.
Bepotastine Besylate
Bepotastine is a histamine H1 receptor anatagonist. Bepotastine suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus). Group: Biochemicals. Alternative Names: 4-[(S)-(4-Chlorophenyl)-2-pyridinylmethoxy]-1-piperidinebutanoic Acid Benzenesulfonate; (S) -4-[4- (4-Chlorophenyl-2-pyridylmethoxy) piperidinyl]butyric Acid Benzenesulfonate; BB; Bepotastine Benzenesulfonate; Bepotastine Benzenesulfonate Salt; Bepotastine Besilate; Bepreve; TAU 284; Talion. Grades: Highly Purified. CAS No. 190786-44-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Bepotastine Besylate
Bepotastine is a histamine H1 receptor antagonist. Bepotastine has been approved in Japan for the treatment of allergic rhinitis and uriticaria/puritus. Synonyms: Bepotastine besylate; Bepreve; Betotastine besilate; Talion; 4-[(S)-(4-chlorophenyl)-2-pyridinylmethoxy]-1-piperidinebutanoic acid, monobenzenesulfonate. Grade: >98%. CAS No. 190786-44-8. Molecular formula: C27H31ClN2O6S. Mole weight: 547.063.
Bepotastine Isopropyl Ester
Bepotastine Isopropyl Ester. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00961. Format: Neat.
Bepotastine N-Butyl Ester
Bepotastine N-Butyl Ester. Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00962. Format: Neat.
(R)-Bepotastine
(R)-bepotastine is an exemplary, potent and selective antagonist of histamine h1 receptors, employed profusely in the research of perennial symptoms of allergic rhinitis, encompassing excessive sneezing, pervasive itching and nasal discharges. Synonyms: 1-Piperidinebutanoic acid, 4-[(4-chlorophenyl)-2-pyridinylmethoxy]-, (R)-; 1-Piperidinebutanoic acid, 4-[(R)-(4-chlorophenyl)-2-pyridinylmethoxy]-; (R)-Bepotastine. Grade: > 95%. CAS No. 190730-41-7. Molecular formula: C21H25ClN2O3. Mole weight: 388.90.
2-[ (4-Chlorophenyl) (4-piperidinyloxy) methyl]pyridine is an intermediate in the synthesis of Bepotastine besylate (B317000), a non-sedating H1-antagonist that has anti-inflammatory activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 122368-54-1. Pack Sizes: 2.5g, 10g. Molecular Formula: C17H19ClN2O. US Biological Life Sciences.
An impurity of Bepotastine besylate, a histamine H1 receptor antagonist that has been approved in Japan for the treatment of allergic rhinitis and uriticaria/puritus. Synonyms: 2-[(S)-(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine L-Tartrate. CAS No. 210095-58-2. Molecular formula: C17H19ClN2O.C4H6O6. Mole weight: 452.89.
2-[ (S) - (4-Chlorophenyl) (4-piperidinyloxy) methyl]pyridine L-Tartrate
2-[ (S) - (4-Chlorophenyl) (4-piperidinyloxy) methyl]pyridine (2R,3R)-2,3-dihydroxybutanedioate is used as a reagent to prepare optically active 4-[ (4-chlorophenyl-2-pyridyl) methoxy]piperidine, a compound that is used as an intermediate in the synthesis of antihistamines and antiallergy agents. (S) -2-[ (4-Chlorophenyl) (4-piperidinyloxy) methyl]pyridine is also an intermediate of Bepotastine besylate (B317000), a non-sedating H1-antagonist that has anti-inflammatory activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 210095-58-2. Pack Sizes: 5g, 25g. Molecular Formula: C21H25ClN2O7. US Biological Life Sciences.
Worldwide
Carbinoxamine Impurity A
α-(4-Chlorophenyl)-2-pyridinemethanol is used as a reagent in the synthesis of Carbinoxamine), a histamine H1 antagonist. α-(4-Chlorophenyl)-2-pyridinemethanol is also an intermediate in the synthesis of Bepotastine besylate, a non-sedating H1-antagonist that has anti-inflammatory activity. Synonyms: α-(p-Chlorophenyl)-2-pyridinemethanol; (p-Chlorophenyl)(2-pyridinyl)methanol; NSC 31264; NSC 47970. Grade: > 95%. CAS No. 27652-89-7. Molecular formula: C12H10ClNO. Mole weight: 219.67.
An impurity of Bepotastine besylate, a histamine H1 receptor antagonist that has been approved in Japan for the treatment of allergic rhinitis and uriticaria/puritus. Synonyms: Pyridine, 2-[(S)-(4-chlorophenyl)(4-piperidinyloxy)methyl]-; (S)-2-[(4-Chlorophenyl)(4-piperidinyloxy)methyl]pyridine. Grade: 95%. CAS No. 201594-84-5. Molecular formula: C17H19ClN2O. Mole weight: 302.80.
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