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Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species ( ROS ) generation and inhibits DNA topoisomerase. Antineoplastic properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Natural Yellow 18 chloride. CAS No. 633-65-8. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-18258.
Berberine chloride
Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Berberine hydrochloride. Product Category: Inhibitors. Appearance: Solid. CAS No. 633-65-8. Molecular formula: C20H18ClNO4. Mole weight: 371.8. Purity: 95%+. Canonical SMILES: COC1=C(OC)C2=C[N+]3=C(C(C(CC3)=C4)=CC5=C4OCO5)C=C2C=C1.[Cl-]. Product ID: ACM633658. Alfa Chemistry ISO 9001:2015 Certified.
A highly potent and selective oxysterol EBI2 (GPR183) agonist (Kd) = 450pM in a saturation binding assay, and EC50 = 140 pM over EC50 = 2.1nM for its enantiomer, 7b,25-OHC, in a GTP-gamma S binding assay). Dose-dependently suppresses forskolin-induced cAMP accumulation in an EBI2-expressing SK-N-MC/CRE-b-galactosidase cell line (IC50 = 2nM), but not in control cells. Stimulates migration of LPS-activated spleen B-cells and anti-CD3/CD28-activated CD4+ T-cells in a dose-dependent manner. In addition, pharmacological inhibition of its biosynthesis in vivo by Clotrimazole, a CYP7B1inhibitor, promotes the migration of adoptively transferred pre-activated B cells to the T/B boundary, mimicking the phenotype of pre-activated B cells in EBI2-deficient mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 25mg. US Biological Life Sciences.
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Berberine chloride hydrate
25g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C20H18ClNO4 ·xH2O. CAS No. 141433-60-5. Prepack ID 89981875-25g. Molecular Weight 371.81. See USA prepack pricing.
Berberine chloride hydrate
Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. Berberine chloride hydrate induces reactive oxygen species ( ROS ) generation and inhibits DNA topoisomerase. Antineoplastic properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Natural Yellow 18 chloride hydrate. CAS No. 68030-18-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-17577.
An isoquinoline alkaloid that acts as an anticancer agent. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. It induces the most potent apoptosis in acute lymphoblastic leukemia (ALL) cells with both MDM2 overexpression and a wild-type (wt)-p53, whereas no pro-apoptotic effect was detected in ALL cells that were negative for MDM2 and wt-p53. Group: Biochemicals. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Berberine Hydrochloride
An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs. Group: Biochemicals. Alternative Names: 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride; Berberine Chloride; 7, 8, 13, 13a-Tetradehydro-9, 10-dimethoxy-2, 3- (methylenedioxy) berbinium Chloride; Berberine Hydrochloride; NSC 646666. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 25g. US Biological Life Sciences.
Worldwide
Berberrubine chloride
Berberrubine chloride is an orally active metabolite of berberine. Berberrubine chloride alleviates mucosal lesions and inflammation in mouse colitis models. Berberrubine chloride has anti-inflammatory, anti-tumor, and antiviral activities [1] [1] [3]. Uses: Scientific research. Group: Natural products. CAS No. 15401-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125850.
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