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| Product | Description | |
|---|---|---|
| Berberine chloride | Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species ( ROS ) generation and inhibits DNA topoisomerase. Antineoplastic properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Natural Yellow 18 chloride. CAS No. 633-65-8. Pack Sizes: 10 mM * 1 mL; 5 g; 10 g. Product ID: HY-18258. |  |
| Berberine chloride | Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Berberine hydrochloride. Product Category: Inhibitors. Appearance: Solid. CAS No. 633-65-8. Molecular formula: C20H18ClNO4. Mole weight: 371.8. Purity: 95%+. Canonical SMILES: COC1=C(OC)C2=C[N+]3=C(C(C(CC3)=C4)=CC5=C4OCO5)C=C2C=C1.[Cl-]. Product ID: ACM633658. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Berberine chloride | Pharmaceutical Secondary Standard; Certified Reference Material. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: NSC 646666, Berberine, chloride,Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride, Berberine hydrochloride, Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride, NSC 163088, Berberinium chloride. |  |
| Berberine Chloride (Berberine) | A highly potent and selective oxysterol EBI2 (GPR183) agonist (Kd) = 450pM in a saturation binding assay, and EC50 = 140 pM over EC50 = 2.1nM for its enantiomer, 7b,25-OHC, in a GTP-gamma S binding assay). Dose-dependently suppresses forskolin-induced cAMP accumulation in an EBI2-expressing SK-N-MC/CRE-b-galactosidase cell line (IC50 = 2nM), but not in control cells. Stimulates migration of LPS-activated spleen B-cells and anti-CD3/CD28-activated CD4+ T-cells in a dose-dependent manner. In addition, pharmacological inhibition of its biosynthesis in vivo by Clotrimazole, a CYP7B1inhibitor, promotes the migration of adoptively transferred pre-activated B cells to the T/B boundary, mimicking the phenotype of pre-activated B cells in EBI2-deficient mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Berberine chloride hydrate | 25g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C20H18ClNO4 ·xH2O. CAS No. 141433-60-5. Prepack ID 89981875-25g. Molecular Weight 371.81. See USA prepack pricing. |  |
| Berberine chloride hydrate | Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. Berberine chloride hydrate induces reactive oxygen species ( ROS ) generation and inhibits DNA topoisomerase. Antineoplastic properties [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Natural Yellow 18 chloride hydrate. CAS No. 68030-18-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-17577. | |
| Berberine chloride hydrate | The plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways regulated by this compound is needed to define the mechanism of its action in cancer treatment. In this review, the molecular targets of berberine in various cancers, particularly breast cancer, are discussed. Berberine was shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells. Some signaling pathways affected by berberine, including the MAP (mitogen-activated protein) kinase and Wnt/β-catenin pathways, are critical for reducing cellular migration and sensitivity to various growth factors. Treatment with BBR(Berberine) in rats on the atherogenic diet reduced plasma total cholesterol and nonHDL cholesterol levels by 29%-33% and 31%-41%, respectively, with no significant differences being observed among the three doses. Berberine induced both apoptotic and autophagic death of HepG2 cells, which was associated with a significant activation of AMPK and an increased expression of the inactive form of acetyl-CoA carboxylase (ACC). Berberine did not show major effects on viability of HEK-293 embryonic kidney and HCT116 colon carcinoma cells and was not toxic in concentrations up to 20 μM. Berberine inhibited β-catenin transcriptional activity and attenuated anchorage-independent growth. As a result of berberine treatment, cellular levels of active β-catenin were reduced concomitant with an increase in the expression of E-cadherin. Synonyms: Natural Yellow 18. Grades: >98%. CAS No. 141433-60-5. Molecular formula: C20H18ClNO4. Mole weight: 371.81. |  |
| Berberine Chloride (Natural Yellow 18, 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium) | An isoquinoline alkaloid that acts as an anticancer agent. It inhibits cell growth and induces apoptosis in a variety of cancer cell lines. It induces the most potent apoptosis in acute lymphoblastic leukemia (ALL) cells with both MDM2 overexpression and a wild-type (wt)-p53, whereas no pro-apoptotic effect was detected in ALL cells that were negative for MDM2 and wt-p53. Group: Biochemicals. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Berberine hydrochloride | Berberine hydrochloride is an isoqinoline alkaloid and acts as a COX-2 inhibitor that exhibits chemopreventive activity against colon tumor formation. Study in humans and hamsters shows that berberine reduces total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides. It also inhibits c-Jun and suppresses inflammation and cancers. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Berberine chloride; Natural Yellow 18; Benzodioxide; Berberinium chloride. Grades: ≥ 98%. CAS No. 633-65-8. Molecular formula: C20H18ClNO4. Mole weight: 371.817. | |
| Berberine Hydrochloride | An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs. Group: Biochemicals. Alternative Names: 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride; Berberine Chloride; 7, 8, 13, 13a-Tetradehydro-9, 10-dimethoxy-2, 3- (methylenedioxy) berbinium Chloride; Berberine Hydrochloride; NSC 646666. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
| Berberrubine chloride | Berberrubine chloride is an orally active metabolite of berberine. Berberrubine chloride alleviates mucosal lesions and inflammation in mouse colitis models. Berberrubine chloride has anti-inflammatory, anti-tumor, and antiviral activities [1] [1] [3]. Uses: Scientific research. Group: Natural products. CAS No. 15401-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125850. | |
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