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| Product | Description | |
|---|---|---|
| 2-Methoxythiophenol | 2-Methoxythiophenol is used in the synthesis of berberine-thiophenyl hybrids as multifunctional agents. Inhibition of acetylcholinesterase, butyrylcholinesterase and AB aggregation antioxidant activity. Group: Biochemicals. Alternative Names: 2-(Methoxy)benzothiol; 2-Mercaptoanisole; 2-Methoxybenzenethiol; 2-Methoxythiophenol; o-Methoxybenzenethiol; o-Methoxythiophenol. Grades: Highly Purified. CAS No. 7217-59-6. Pack Sizes: 5g. US Biological Life Sciences. |  Worldwide |
| Berberine hydrogen sulphate | Berberine is a natural compound that has been shown to have anti-inflammatory and anticancer properties. It is the main component of berberine sulfate, which can be found in plants such as Coptis chinensis and goldenseal. Berberine sulfate has been shown to inhibit skin tumor formation by inhibiting nuclear DNA synthesis and tumor cell growth. Berberine sulfate also inhibits the production of p-nitrophenyl phosphate, a chemical that is used as an indicator for bacterial growth. Berberine sulfate binds to DNA polymerase and inhibits its activity, thereby preventing transcription of DNA into RNA. This compound can be used in chromatographic analysis and optical sensor systems to detect bacterial infections. Group: Other alkaloids. Alternative Names: Natural Yellow 18. CAS No. 633-66-9. Molecular formula: C20H18NO4·HSO4. Mole weight: 433.43 g/mol. Canonical SMILES: COC1=C (C2=C[N+]3=C (C=C2C=C1)C4=CC5=C (C=C4CC3)OCO5)OC. OS (=O) (=O)[O-]. Catalog: ACM633669. |  |
| berberine reductase | Involved in alkaloid biosynthesis in Corydalis cava to give (R)-canadine with the opposite configuration to the precursor of berberine (see EC 1.3.3.8 tetrahydroberberine oxidase). Also acts on 7,8-dihydroberberine. Group: Enzymes. Synonyms: (R)-canadine synthase. Enzyme Commission Number: EC 1.5.1.31. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1513; berberine reductase; EC 1.5.1.31; (R)-canadine synthase. Cat No: EXWM-1513. |  |
| columbamine oxidase | An iron protein. Oxidation of the O-methoxyphenol structure forms the methylenedioxy group of berberine. Group: Enzymes. Synonyms: berberine synthase. Enzyme Commission Number: EC 1.21.3.2. CAS No. 95329-18-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1249; columbamine oxidase; EC 1.21.3.2; 95329-18-3; berberine synthase. Cat No: EXWM-1249. | |
| Jatrorrhizine hydrochloride | Jatrorrhizine hydrochloride is a naturally occurring compound, which has been shown to have hypoglycemic effects and can be used for the treatment of skin cancer. It is an analogue of berberine that inhibits mitochondrial membrane potential, leading to cell death by inhibiting energy metabolism and causing chromatographic analysis. Jatrorrhizine hydrochloride also inhibits the synthesis of proteins required for glycolysis, including hexokinase 2 (HK2), phosphofructokinase 1 (PFK1), and pyruvate kinase M2 (PKM2). This drug is metabolized by esterases or glucuronidases to form benzalkonium chloride or ginsenoside RG3. This active form binds to penicillin-binding protein, which may lead to metabolic disorders such as hepatic steatosis. Group: Other alkaloids. CAS No. 2106804-01-5. Molecular formula: C20H20NO4·HCl. Mole weight: 374.84 g/mol. Canonical SMILES: COC1=C (C2=C[N+]3=C (C=C2C=C1)C4=CC (=C (C=C4CC3)O)OC)OC. [Cl-]. Catalog: ACM2106804015. | |
| reticuline oxidase | Contains FAD. The enzyme from the plant Eschscholtzia californica binds the cofactor covalently. Acts on (S)-reticuline and related compounds, converting the N-methyl group into the methylene bridge ('berberine bridge') of (S)-tetrahydroprotoberberines. The product of the reaction, (S)-scoulerine, is a precursor of protopine, protoberberine and benzophenanthridine alkaloid biosynthesis in plants. Group: Enzymes. Synonyms: BBE; berberine bridge enzyme; berberine-bridge-forming enzyme; tetrahydroprotoberberine synthase. Enzyme Commission Number: EC 1.21.3.3. CAS No. 152232-28-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1250; reticuline oxidase; EC 1.21.3.3; 152232-28-5; BBE; berberine bridge enzyme; berberine-bridge-forming enzyme; tetrahydroprotoberberine synthase. Cat No: EXWM-1250. | |
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