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| Product | Description | |
|---|---|---|
| Berubicin | Berubicin has potential antineoplastic activity. Berubicin intercalates into DNA and interrupts topoisomerase II activity, resulting in the inhibition of DNA replication and repair, and RNA and protein synthesis. Synonyms: Daunorubicin Impurity 9; RTA 744; RTA-744; RTA744; WP 769; WP769; WP-769; 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(phenylmethyl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-. Grades: ≥95% by HPLC. CAS No. 677017-23-1. Molecular formula: C34H35NO11. Mole weight: 633.65. |  |
| Berubicin | Berubicin (RTA 744 free base; WP 744) is a 4'-O-benzyldoxorubicin that inhibits P-gp and MRP1-mediated efflux and has anticancer activity. Berubicin inhibits glioblastoma multiforme (GBM) and exhibits cytotoxicity. Berubicin has poor bioavailability in mice [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RTA 744 free base; WP 744 free base; WP 769. CAS No. 677017-23-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-14942. |  |
| Berubicin hydrochloride | Berubicin hydrochloride (RTA 744) is a Doxorubicin (HY-15142A) analogue. Berubicin hydrochloride triggers apoptosis and cell killing in NB cells by activating proapoptotic mediators. Berubicin hydrochloride has proapoptotic and anti-leukemia activities. Berubicin hydrochloride can be used for cancer research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RTA 744; WP 744; WP 769 hydrochloride. CAS No. 293736-67-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-14942A. | |
| Berubicin Hydrochloride | Berubicin hydrochloride is the hydrochloride of berubicin, which is an anthracycline derivative used as a topoisomerase II inhibitor with activity in ependymoma. Berubicin hydrochloride has potential antineoplastic activity. Uses: A topoisomerase ii inhibitor with activity in ependymoma. Synonyms: Daunorubicin Impurity 9 hydrochloride; RTA 744 hydrochloride; WP 769 hydrochloride; 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-(phenylmethyl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)-, hydrochloride (1:1). Grades: ≥95%. CAS No. 293736-67-1. Molecular formula: C34H35NO11.HCl. Mole weight: 670.10. | |
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