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| Product | Description | |
|---|---|---|
| GALC, Positive Control (Galactocerebrosidase, GALCERase, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase) | GALC, Positive Control (Galactocerebrosidase, GALCERase, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase). Group: Molecular Biology. Pack Sizes: 15ul. US Biological Life Sciences. |  Worldwide |
| 1,2,4,6-Tetra-O-acetyl-3-deoxy-3-phthalimido-D-galactopyranoside | 1,2,4,6-Tetra-O-acetyl-3-deoxy-3-phthalimido-D-galactopyranoside - a chemical of interest in the field of pharmaceutical research - is an agent that has demonstrated the inhibition of beta-galactosidase activity. Its potential role in the treatment of GM1 gangliosidosis, a disorder associated with lysosomal storage, remains an area of active investigation. By considering its properties, 1,2,4,6-tetra-O-acetyl-3-deoxy-3-phthalimido-D-galactopyranoside may offer meaningful insights into the therapeutic approaches in lysosomal storage disorders. Molecular formula: C22H23NO11. Mole weight: 477.42. |  |
| 2-Fluoro-4-nitrophenyl b-D-galactopyranoside | 2-Fluoro-4-nitrophenyl b-D-galactopyranoside is a valuable compound widely used in biomedical research. This compound acting as an advanced recompound for the detection of beta-galactosidase activity in cells and tissues. It finding applications in drug discovery and development, aiding the study of diseases such as cancer and neurodegenerative disorders. Synonyms: β-D-Galactopyranoside, 2-fluoro-4-nitrophenyl; 2-Fluoro-4-nitrophenyl β-D-galactopyranoside. CAS No. 807610-60-2. Molecular formula: C12H14FNO8. Mole weight: 319.24. | |
| 3-Carboxyumbelliferyl b-D-galactoside BSA conjugate | 3-Carboxyumbelliferyl b-D-galactoside BSA conjugate is a conjugate of BSA (bovine serum albumin, MW = 66.4K) and β-galactosidase substrate carboxyumbellliferyl β-D-galactoside ab275363. It produces a protein that can be used to measure extracellular beta-galactosidase activity, measuring lacY penetrase activity. It is also used for microinjection analysis, or to measure cell destruction or lysis. | |
| 3-Indolyl b-D-galactopyranoside | 3-Indolyl b-D-galactopyranoside, a synthetic substrate employed in the biomedical sector, is highly efficacious in detecting the existence of beta-galactosidase enzymes. Predominantly utilized as a marker for gene expression and screening in genetic research, this product is not intended for therapeutic purposes and cannot cure any ailment. Complex and nuanced, this substrate is an indispensable tool for conducting quality research in the field of biomedicine. Synonyms: 3-Indoxyl b-D-galactopyranoside; 1H-Indol-3-yl β-D-galactopyranoside; (2S,3R,4S,5R,6R)-2-((1H-Indol-3-yl]oxy]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; Indol-3-ol β-D-galactopyranoside; Indoxyl β-D-galactoside. CAS No. 126787-65-3. Molecular formula: C14H17NO6. Mole weight: 295.29. | |
| 3-Keto-N-aminoethyl-N-aminocaproyldi hydrocinnamoyl Cyclopamine (KAAD-Cyclopamine) | Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and sonic hedgehog intracellular signaling. The KAAD derivative has shown 10-20 fold higher potency than cyclopamine in inhibition of beta-Galactosidase expression in Ptch(-/-) cells. Group: Biochemicals. Alternative Names: KAAD-Cyclopamine. Grades: Highly Purified. CAS No. 306387-90-6. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| 4-Methylumbelliferyl 2-Acetamido-2-deoxy-3,4-di-O-benzoyl-β-D-Galactopyranoside 6-Sulfate | 4-Methylumbelliferyl 2-Acetamido-2-deoxy-3,4-di-O-benzoyl-β-D-Galactopyranoside 6-Sulfate is a potent substrate commonly used in biomedical research. It is utilized for the detection and quantification of lysosomal enzymes, particularly beta-galactosidase, aiding in the diagnosis and monitoring of various diseases such as lysosomal storage disorders. Its unique structure allows for precise and sensitive measurement of enzyme activity, making it an essential tool in the biomedicine field. Synonyms: 7-[[2-(Acetylamino)-3,4-di-O-benzoyl-2-deoxy-6-O-sulfo-α-D-glucopyranosyl]oxy]-4-methyl-2H-1-benzopyran-2-one. CAS No. 154639-33-5. Molecular formula: C32H29NO13S. Mole weight: 667.64. | |
| 4-Methylumbelliferyl b-D-lactoside | 4-Methylumbelliferyl b-D-lactoside, a substrate widely utilized in the biomedical sector, is employed for detecting beta-galactosidase enzyme activity. The latter serves an utmost importance in the lysosomal storage disorders and lactose intolerance study. Following cleaving of 4-Methylumbelliferyl b-D-lactoside by beta-galactosidase, an irradiant product is released, whose measurement allows for quantified enzyme activity assessment. Synonyms: MUL; 4-MU-b-D-Lactoside; 7-[(4-O-β-D-Galactopyranosyl-β-D-glucopyranosyl)oxy]-4-methyl-2H-1-benzopyran-2-one; 4-Methylumbelliferyl-β-D-lactoside; 4-Methylumbelliferyl beta-D-lactopyranoside. CAS No. 84325-23-5. Molecular formula: C22H28O13. Mole weight: 500.45. | |
| 5-Acetamidofluorescein-di-(b-D-galactopyranoside) | 5-Acetamidofluorescein-di-(b-D-galactopyranoside) exemplifies an indispensable entity in the realm of biomedicine, pervasively employed across multifarious domains. Recognized as AFG-beta-gal, this compound assumes pivotal significance as a substrate in scrutinizing gene expression and appraising assays. Manifesting its prowess in unveiling the intricacies of the beta-galactosidase enzyme, it allows researchers to decipher gene regulation and the associated cellular mechanisms. Synonyms: C2FDG; 2-Acetylaminofluorescein-di-(b-D-galactopyranoside); N-[3',6'-Bis(β-D-galactopyranosyloxy)-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl]acetamide; N-(3-Oxo-3',6'-bis(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)acetamide. CAS No. 216299-45-5. Molecular formula: C34H35NO16. Mole weight: 713.65. | |
| 5-Bromo-4-chloro-3-indolyl b-D-fucopyranoside | 5-Bromo-4-chloro-3-indolyl b-D-fucopyranoside, a ubiquitous substrate in molecular and cell biology, is utilized as a tool to indicate the presence of beta-galactosidase in the targeted cells. Upon cleavage by the enzyme, the formerly dormant substrate induces a conspicuously blue hue that unmistakably confirms gene expression and sheds light on cellular localization. Synonyms: X-b-D-Fucoside; 5-Bromo-4-chloro-3-indoxyl-beta-D-fucopyranoside; (2S,3R,4S,5R,6R)-2-((5-Bromo-4-chloro-1H-indol-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol; 5-Bromo-4-chloro-1H-indol-3-yl 6-deoxy-β-D-galactopyranoside; Galactopyranoside, 5-bromo-4-chloroindol-3-yl 6-deoxy-, β-D-; 5-Bromo-4-chloroindol-3-yl-β-D-fucopyranoside. CAS No. 17016-46-5. Molecular formula: C14H15BrClNO5. Mole weight: 392.63. | |
| (8-Ethoxycarbonyloctyl)-2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside | (8-Ethoxycarbonyloctyl)-2,3,4,6-tetra-O-acetyl-b-D-galactopyranoside, a chemical compound of paramount significance in glycobiology, has gained immense popularity due to its efficacy in glycoprotein research. Known for its high specificity and precision, this derivative of beta-galactosidase has paved the way for significant advancements in the field by serving as a powerful tool for the detection and modification of glycoproteins. Its proven efficiency has made it a widely acclaimed compound among researchers, and a cornerstone of glycoprotein-related studies. Molecular formula: C24H38O12. Mole weight: 518.55. | |
| beta-Gal-Et-N3 | beta-Gal-Et-N3 is an indispensable compound, finding multifarious applications steming from its remarkable utility in exploring the intricate world of glycosylation and galactosyltransferase activity. Possessing an unparalleled chemical architecture, this remarkable compound facilitates the exclusive marking and observation of beta-galactosidase enzymes, thereby significantly contributing to the identification and research of afflictions like cancer and lysosomal storage disorders. Synonyms: 1-(2-Azidoethoxy)-beta-D-galactopyranose; (2R,3R,4S,5R,6R)-2-(2-azidoethoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; 1-O-2-azidoethyl-beta-d-galactose. CAS No. 151651-54-6. Molecular formula: C8H15N3O6. Mole weight: 249.22. | |
| beta-Gal-TEG-N3 | beta-Gal-TEG-N3 is a biomedical product that plays a critical role in the field of drug delivery and diagnostics. It is commonly used as a linker molecule for the conjugation of beta-galactosidase enzymes to various drugs and imaging agents. This enables targeted delivery and localization of therapeutic and diagnostic substances for the treatment and detection of specific diseases, including cancers and genetic disorders. Synonyms: 1-O-(2-(2-(2-Azidoethoxy)ethoxy)ethoxy)-beta-D-galactopyranoside; (2R,3R,4S,5R,6R)-2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. CAS No. 126765-27-3. Molecular formula: C12H23N3O8. Mole weight: 337.33. | |
| Blood-group endo-β-galactosidase 98A from Streptococcus pneumoniae, Recombinant | Blood-group-substance endo-1,4-beta-galactosidase (EC 3.2.1.102, endo-beta-galactosidase, blood-group-substance 1,4-beta-D-galactanohydrolase) is an enzyme with systematic name blood-group-substance 4-beta-D-galactanohydrolase.[1][2][3] This enzyme catalyses the following chemical reaction: Endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances. Hydrolyses the 1,4-beta-D-galactosyl linkages adjacent to a 1,3-alpha-D-galactosyl or N-acetylgalactosaminyl residues and a 1,2-alpha-D-fucosyl residue. Group: Enzymes. Synonyms: Blood-group-substance endo-1,4-beta-galactosidase; EC 3.2.1.102; endo-beta-galactosidase; blood-group-substance 1,4-beta-D-galactanohydrolase. Enzyme Commission Number: EC 3.2.1.102. CAS No. 52720-51-1. Purity: >90% by SDS-PAGE. Endo-β-galactosidase. Mole weight: 69.7 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Streptococcus pneumoniae. Blood-group-substance endo-1,4-beta-galactosidase; EC 3.2.1.102; endo-beta-galactosidase; blood-group-substance 1,4-beta-D-galactanohydrolase; Blood-group endo-β-galactosidase 98A. Cat No: NATE-1411. |  |
| C12FDG | C12FDG (5-Dodecanoylaminofluorescein di-?-D-Galactopyranoside) is a lipophilic green fluorescent substrate for ?-galactosidase detection. C12-FDG is more sensitive than Fluorescein di(?-D-galactopyranoside) (HY-101895) for beta-galactosidase activity determinations in animal cells (Ex/Em = 488/523 nm)[1]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 5-Dodecanoylaminofluorescein di-?-D-Galactopyranoside. CAS No. 138777-25-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126839. |  |
| Galactan 1,3-β-galactosidase from Clostridium thermocellum, Recombinant | Galactan 1,3-beta-galactosidase (EC 3.2.1.145, galactan (1->3)-beta-D-galactosidase) is an enzyme with system name galactan 3-beta-D-galactosidase. This enzyme catalyses the following chemical reaction: Hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans. This enzyme removes not only free galactose, but also 6-glycosylated residues. Group: Enzymes. Synonyms: Exo-β-1,3-galactosidase; galactan 3-β-D-galactosidase; exo-beta-1,3-galactosidase; galactan 1,3-beta-galactosidase; galactan 3-betaD-galactosidase. Enzyme Commission Number: EC 3.2.1.145. CAS No. 161515-48-6. Purity: > 95 % as judged by SDS-PAGE. Galactan 1,3-β-galactosidase. Mole weight: 37692 Da. Activity: 20 U/mg. Storage: Store at -20°C (shipped at room temperature). Form: Lyophilised powder. Source: Clostridium thermocellum ATCC 27405. Exo-β-1,3-galactosidase; galactan 3-β-D-galactosidase; exo-beta-1,3-galactosidase; galactan 1,3-beta-galactosidase; galactan 3-betaD-galactosidase; Galactan 1,3-β-galactosidase; EC 3.2.1.145. Cat No: NATE-1206. | |
| Golgicide A | Golgicide A is a potent, highly specific, and reversible inhibitor of the cis-Golgi ADP-ribosylation factor guanine nucleotide exchange factors (ArfGEF) GBF1. Golgicide A inhibited HSV-1 entry via beta-galactosidase reporter assay and impaired incoming virus transport to the nuclear periphery. Synonyms: GCA; (3aR,9bS)-rel-6,8-Difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-3H-cyclopenta[c]quinoline; 3H-Cyclopenta[c]quinoline, 6,8-difluoro-3a,4,5,9b-tetrahydro-4-(3-pyridinyl)-, (3aR,9bS)-. Grade: ≥98%. CAS No. 1139889-93-2. Molecular formula: C17H14F2N2. Mole weight: 284.30. | |
| Golgicide A | Golgicide A is a Potent, selective and reversible inhibitor of GBF1 ArfGEF. Golgicide A inhibited HSV-1 entry via beta-galactosidase reporter assay and impaired incoming virus transport to the nuclear periphery. Inhibition of GBF1 via golgicide A can result in rapid dissociation of COPI vesicle coat protein from Golgi membranes and disassembly of the Golgi and trans-Golgi network. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Golgicide A; GCA. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1139889-93-2. Molecular formula: C17H14F2N2. Mole weight: 284.31. Purity: >98%. IUPACName: (3aR,9bS)-6,8-difluoro-4-(pyridin-3-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline. Canonical SMILES: FC4=CC([C@]3([H])[C@]([H])2CC=C3)=C(C(F)=C4)NC2C1=CN=CC=C1. Product ID: ACM1139889932. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Maltotriose | Maltotriose, the second most abundant sugar present in brewing, is an inducer of the maltose regulon of Escherichia coli. Maltotriose can induce beta-galactosidase synthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 1109-28-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-113011. | |
| Muristerone A | Muristerone A is a potent member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. An analog of ecdysone with similar properties to Ponasterone A. Inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals.Induces apoptosis in cells transfected with wild-type Bax. Induces expression of beta-galactosidase. Stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells. Insect steroid hormone involved in regulating metamorphosis, causing a response to G2 cell cycle arrest. Major molting hormone in some insects. Has protective effects in plants.Source:Ipomoea hederacea seeds. Group: Biochemicals. Alternative Names: 2beta, 3beta, 5beta, 11alpha, 14alpha, 20R, 22R-Heptahydroxycholest-7-en-6-one. Grades: Highly Purified. CAS No. 38778-30-2. Pack Sizes: 250ug, 1mg. Molecular Formula: C27H44O8, Method for Determining. US Biological Life Sciences. | Worldwide |
| Native Kluyveromyces lactis β-Galactosidase | β-galactosidase, also called beta-gal or β-gal, is a hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides. SubstRates of different β-galactosidases include ganglioside GM1, lactosylceramides, lactose, and various glycoproteins. A β-galactosidase preparation produced by submerged fermentation of a selected strain of the yeast kluyveromyces lactis. Applications: Lactose was hydrolyzed to monosaccharides using β-galactosidase from kluyveromyces fragilis. Group: Enzymes. Synonyms: Beta-Galactosidase; Galactosidase; lactase; β-lactosidase; maxilact; hydrolact; β-D-lactosidase; S 2107; lactozym; trilactase; β-D-galactanase; oryzatym; sumiklat. CAS No. 9031-11-2. β-gal. Activity: > 2600 units/g. Source: Kluyveromyces lactis. Beta-Galactosidase; Galactosidase; lactase; β-lactosidase; maxilact; hydrolact; β-D-lactosidase; S 2107; lactozym; trilactase; β-D-galactanase; oryzatym; sumiklat. Cat No: NATE-0297. | |
| Native Pseudomonas sp. Keratanase | Keratan-sulfate endo-1,4-beta-galactosidase (EC 3.2.1.103, endo-beta-galactosidase, keratan sulfate endogalactosidase, keratanase, keratan-sulfate 1,4-beta-D-galactanohydrolase) is an enzyme with system name keratan-sulfate 4-beta-D-galactanohydrolase. This enzyme catalyses the following chemical reaction:Endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate. Hydrolyses the 1,4-beta-D-galactosyl linkages adjacent to 1,3-N-acetyl-alpha-D-glucosaminyl residues. Group: Enzymes. Synonyms: Endo-β-galactosidase; endo-β-galactosidase; keratan sulfate endogalactosidase; keratanase; keratan-sulfate 1,4-β-D-galactanohydrolase; EC 3.2.1.103. Enzyme Commission Number: EC 3.2.1.103. CAS No. 55072-01-0. Endo-β-galactosidase. Storage: -20°C. Form: lyophilized powder. Source: Pseudomonas sp. Endo-β-galactosidase; endo-β-galactosidase; keratan sulfate endogalactosidase; keratanase; keratan-sulfate 1,4-β-D-galactanohydrolase; EC 3.2.1.103. Pack: vial of >10 units. Cat No: NATE-0364. | |
| Native Thermus brockianus β-Galactosidase | β-galactosidase, also called beta-gal or β-gal, is a hydrolase enzyme that catalyzes the hydrolysis of β-galactosides into monosaccharides. SubstRates of different β-galactosidases include ganglioside GM1, lactosylceramides, lactose, and various glycoproteins. The enzyme hydrolyses terminal, non-reducing b-d-galactose residues in b-d-galactosides. Group: Enzymes. Synonyms: Beta-Galactosidase; Galactosidase; lactase; β-lactosidase; maxilact; hydrolact; β-D-lactosidase; S 2107; lactozym; trilactase; β-D-galactanase; oryzatym; sumiklat. CAS No. 9031-11-2. β-gal. Source: Thermus brockianus. Beta-Galactosidase; Galactosidase; lactase; β-lactosidase; maxilact; hydrolact; β-D-lactosidase; S 2107; lactozym; trilactase; β-D-galactanase; oryzatym; sumiklat. Cat No: NATE-0298. | |
| Smo Antagonist, SA10 (4- ( (Benzo [c] [1, 2, 5] thiadiazole-4-sulfonamido) methyl -N- (3-phenylpropyl ) cyclohexane carboxamide) | SA10 inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC50 = 5uM). However, unlike SA1 and SA9, Smo antagonist SA10 does not directly bind to Smo. Inhibits the localization o Smo to cilia. Also treatment of Ptch1-/- MEFs with SA10 suppresses the beta-galactosidase activity (IC50 = 11.0uM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
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