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Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC 50 of 7.5 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883. CAS No. 1611493-60-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605.
Bictegravir
Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM for strand transfer activity. Bictegravir is a drug of the integrase inhibitor class that was copied from Dolutegravir by scientists at Gilead Sciences. Bictegravir also inhibits HIV-1 viral infection in MT-2 and MT-4 cells, CD4+ T cells, and macrophages (EC50s = 1.5, 2.5, 1.5, and 6.6 nM, respectively) without exhibiting cytotoxicity (CC50s = 10.3, 3.7, 13, and 29.8 μM, respectively). In 2016, bictegravir was in a Phase 3 trial as part of a single tablet regimen in combination with tenofovir alafenamide (TAF) and emtricitabine (FTC) for the treatment of HIV-1 infection. Synonyms: GS-9883; GS 9883; GS9883. Grades: ≥98%. CAS No. 1611493-60-7. Molecular formula: C21H18F3N3O5. Mole weight: 449.39.
Bictegravir Impurity 22
Bictegravir Impurity 22. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,3R)-3-aminocyclopentanol. CAS No. 124555-33-5. Molecular formula: C5H11NO·HCl. Mole weight: 137.61. Catalog: APB124555335.
Bictegravir Impurity 23
Bictegravir Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1S,3S)-3-aminocyclopentanol. CAS No. 1523530-42-8. Molecular formula: C5H11NO·HCl. Mole weight: 137.61. Catalog: APB1523530428.
Bictegravir Related Compound 1
Bictegravir Related Compound 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(2,2-dimethoxyethyl)-5-methoxy-6-(methoxycarbonyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid. CAS No. 1335210-23-5. Molecular formula: C13H17NO8. Mole weight: 315.28. Catalog: APB1335210235.
Bictegravir Related Compound 3
Bictegravir Related Compound 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1S,3R)-3-aminocyclopentanol. CAS No. 1036260-18-0. Molecular formula: C5H11NO. Mole weight: 101.15. Catalog: APB1036260180.
Bictegravir sodium
Bictegravir sodium is a HIV-1 integrase strand transfer inhibitor that is derived from the drug dolutegravir. Synonyms: Bictegravir sodium|1807988-02-8|Bictegravir (sodium)|UNII-4L5MP1Y7W7|4L5MP1Y7W7|sodium;(1S, 11R, 13R)-3, 6-dioxo-7-[(2, 4, 6-trifluorophenyl)methylcarbamoyl]-12-oxa-2, 9-diazatetracyclo[11.2.1.02, 11.04, 9]hexadeca-4, 7-dien-5-olate|Bictegravir sodium [USAN]|Bictegravir sodium (JAN / USAN) |CHEMBL3989867|SCHEMBL 19991461|CHEBI: 172961|BCP20910|HY-17605A|AC-30681|CS-0380750|D10910|N16970|A904622|Q27259 952|GS-9883; GS 9883; GS9883; GS-9883-01; GS9883-01; GS 9883-01|(2R,5S,13aR)-8-Hydroxy-7,9-dioxo-N-((2,4,6-trifluorophenyl)methyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido(1',2':4,5)pyrazino(2,1-b)(1,3)oxazepine-10-carboxamide monosodium salt|2,5-Methanopyrido(1',2':4,5)pyrazino(2,1-b)(1,3)oxazepine-10-carboxamide, 2,3,4,5,7,9,13,13a-octahydro-8-hydroxy-7,9-dioxo-N-((2,4,6-trifluorophenyl)methyl)-, sodium salt (1:1), (2R,5S,13aR)-|Sodium (2R,5S,13aR)-7,9-dioxo-10-((2,4,6-trifluorobenzyl)carbamoyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1, 3]oxazepin-8-olate|sodium (2R,5S,13aR)-7,9-dioxo-10-[(2,4,6-trifluorobenzyl)carbamoyl]-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepin-8-olate. Grades: >98%. CAS No. 1807988-02-8. Molecular formula: C21H17F3N3NaO5. Mole weight: 471.4.
Bictegravir sodium
Bictegravir sodium is a potent inhibitor of HIV-1 integrase , with an IC 50 of 7.5 nM. Bictegravir sodium exhibits potent and selective anti-HIV activity and low cytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9883 sodium. CAS No. 1807988-02-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17605A.
(1R,3S)-3-Aminocyclopentanol
(1R,3S)-3-Aminocyclopentanol is a Bictegravir (1611493-60-7) intermediate and an antiviral agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 1110772-05-8. Pack Sizes: 25mg, 50mg. Molecular Formula: C5H11NO, Molecular Weight: 101.15. US Biological Life Sciences.
Worldwide
2,4,6-Trifluorobenzylamine
2,4,6-Trifluorobenzylamine is a Bictegravir (1611493-60-7) intermediate and an antiviral agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 214759-21-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H6F3N, Molecular Weight: 161.12. US Biological Life Sciences.
Worldwide
BBICT
BBICT. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4- (4, 6-Bis[12-phenylindolo[2, 3- a] carbazol- 11(12H) - yl] - 1, 3, 5- triazin- 2- yl)benzonitrile. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1617496-77-1. Molecular formula: C58H34N8. Mole weight: 842.94 g/mol. Product ID: ACM1617496771. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bictegravir/emtricitabine/tenofovir alafenamide.
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