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| Product | Description | |
|---|---|---|
| Bicyclol | Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C. Synonyms: Bicyclol; SY 801; SY-801; SY801. Grades: >98%. CAS No. 118159-48-1. Molecular formula: C19H18O9. Mole weight: 390.34. |  |
| Bicyclol | Bicyclol (SY801) is an orally active derivative of the traditional Chinese medicine Schisandra chinensis, which has antiviral, anti-inflammatory, immunomodulatory, antioxidant, anti-steatosis, anti-fibrotic and anti-tumor activities. Bicyclol regulates the expression of heat shock proteins and plays an anti- apoptosis role in hepatocytes. Bicyclol reduces the activation of NF-κB and the levels of inflammatory factors in hepatocytes infected with hepatitis C virus (HCV) by inhibiting the activation of the ROS-MAPK-NF-κB pathway, and prevents ferroptosis in acute liver injury. Bicyclol can change the expression of Mdr-1 , GSH/GST and Bcl-2 , increase the intracellular concentration of anticancer drugs, and sensitize drug-resistant cells to anticancer drugs. Bicyclol inhibits the proliferation of human malignant hepatoma cells by regulating the PI3K/AKT pathway and the Ras/Raf/MEK/ERK pathway. Bicyclol can be used in the study of chronic hepatitis, acute liver injury, nonalcoholic fatty liver disease, liver fibrosis and hepatocellular carcinoma [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SY801. CAS No. 118159-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0766. |  |
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