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Bifendate (DDB), extracted from Schisandrae chinensis , is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase (ALT) level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins ( CYPs ) and reverse P-gp -mediated multi-drug resistance (MDR) [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DDB. CAS No. 73536-69-3. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W018791.
Bifendate
Bifendate is a synthetic intermediate of schisandrin C, a dibenzocyclooctadiene derivative derived from lignans used in traditional medicine and also a anti-HBV drug used in the treatment of chronic hepatitis B. It has been used in some countries as a hepatoprotectant adjuvant in the treatment of liver diseases, such as chronic viral hepatitis or drug-induced hepatic damage. Uses: Cytochrome p-450 enzyme inhibitors. Synonyms: 7,7'-Dimethoxy-[4,4'-Bi-1,3-benzodioxole]-5,5'-dicarboxylic Acid 5,5'-Dimethyl Ester; DDB; Dimethyl 4,4'-Dimethoxy-5,6,5',6'-di(methylenedioxy)biphenyl-2,2'-dicarboxylate; Dimethyl dicarboxylate Biphenyl; α-DDB. Grades: 97.0%~103.0%. CAS No. 73536-69-3. Molecular formula: C20H18O10. Mole weight: 418.36.
Bifendate
Bifendate is a synthetic intermediate of Schisandrin C and also a anti-HBV drug used in the treatment of chronic hepatitis B. Group: Biochemicals. Alternative Names: 7,7'-Dimethoxy-[4,4'-Bi-1,3-benzodioxole]-5,5'-dicarboxylic Acid 5,5'-Dimethyl Ester; DDB; DDB; Dimethyl 4, 4'-Dimethoxy-5, 6, 5', 6'-di (methylenedioxy) biphenyl-2, 2'-dicarboxylate; Dimethyl dicarboxylate Biphenyl; Diphenyl Dimethyl Bicarboxylate; α-DDB. Grades: Highly Purified. CAS No. 73536-69-3. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Bifendate-d6
Isotope labelled analogue of Bifendate (B382890), a synthetic intermediate of Schisandrin C and also a anti-HBV drug used in the treatment of chronic hepatitis B. Group: Biochemicals. Alternative Names: 7,7'-Dimethoxy-[4,4'-Bi-1,3-benzodioxole]-5,5'-dicarboxylic Acid 5,5'-Dimethyl Ester-d6; DDB-d6; DDB-d6; Dimethyl 4, 4'-Dimethoxy-5, 6, 5', 6'-di (methylenedioxy) biphenyl-2, 2'-dicarboxylate-d6; Dimethyl dicarboxylate Biphenyl-d6; Diphenyl Dimethyl Bicarboxylate-d6; α-DDB-d6. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Bifendate Dicarboxylic Acid
Bifendate Dicarboxylic Acid. Group: Biochemicals. Alternative Names: 7,7'-Dimethoxy-[4,4'-Bi-1,3-benzodioxole]-5,5'-dicarboxylic Acid. Grades: Highly Purified. CAS No. 105868-34-6. Pack Sizes: 250mg. Molecular Formula: C18H14O10, Molecular Weight: 390.3. US Biological Life Sciences.
Worldwide
Bifendate Impurity A
Bifendate Impurity A is an impurity of bifendate, rendering indispensable utility in the clinical therapy of an array of intricate hepatic pathologies. Grades: > 95%. CAS No. 1181519-47-0. Molecular formula: C18H14O8. Mole weight: 358.31.
Bifendate Impurity B
Bifendate Impurity B is an impurity of Bifendate, a potent therapeutic agent treating chronic hepatitis B. Esteemed for its antiviral prowess and hepatic safeguards, Bifendate efficaciously assuages liver inflammation and diminishes the viral burden inherent in patients afflicted with this pathological viral infestation. Grades: > 95%. CAS No. 128142-41-6. Molecular formula: C18H16O9. Mole weight: 376.32.
Bifendate Impurity E
Bifendate Impurity E is an impurity of Bifendate, facilitating the comprehensive control of multifarious cardiovascular disorders within the biomedical domain. Grades: > 95%. CAS No. 205117-47-1. Molecular formula: C19H16O10. Mole weight: 404.33.
Bifendate Impurity G
Bifendate Impurity G is an impurity of Bifendate used in the therapy of liver diseases. Bifendate is a medication known for its hepatoprotective effects, specifically targeting and helping alleviate symptoms related to liver inflammation and damage caused by conditions such as hepatitis. Synonyms: CHEMBL2087835; 79279-08-6; (7,7'-Dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)dimethanol; (4R)-(7,7'-Dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)dimethanol; (4S)-(7,7'-Dimethoxy-[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)dimethanol; 1395351-58-2. Grades: > 95%. CAS No. 79279-08-6. Molecular formula: C18H18O8. Mole weight: 362.34.
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