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| Product | Description | |
|---|---|---|
| BIIB021 | BIIB021 (CNF2024) is an orally active, fully synthetic inhibitor of HSP90 with a K i and an EC 50 of 1.7 nM and 38 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CNF2024. CAS No. 848695-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10212. |  |
| 6-chloro-9-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-9H-purin-2-amine | BIIB021 is An orally active, purine-scaffold, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. BIIB021 that is currently undergoing Phase II testing, may have broader application against tumors with acquired multidrug resistance or tumors located in organs protected by MDR proteins, such as the adrenal glands, brain and testis. Uses: Biib 021 an orally available, fully synthetic small-molecule inhibitor of the heat shock protein hsp90. studies show that biib 021 adminisitration led to degradation of hsp90 client proteins measured in tumor tissue and resulted in the inhibition of tumor. Synonyms: [6-Chloro-9-(4-methoxy-3,5-dimethylpyridin-2-ylmethyl)-9H-purin-2-yl]amine; CNF-2024; CNF 2024; CNF2024. Grade: >98%. CAS No. 848695-25-0. Molecular formula: C14H15ClN6O. Mole weight: 318.76. |  |
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