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| Product | Description | |
|---|---|---|
| Amisulpride hydrochloride | Amisulpride hydrochloride could inhibit radioligand binding to native dopamine D2 receptor in membranes from the rat striatum with an IC50 value of 21nM. It has been revealed to displace [3H]raclopride binding in vivo with an ED50 value of 17.3±1.86mg/kg in the rat limbic system. It has been noted to inhibit quinpirole-induced [3H]thymidine with an IC50 value of 22±3nM. It is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. It has been approved in February 2002 by FDA. Uses: Amisulpride hydrochloride is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. Synonyms: DAN 2163 hydrochloride; DAN2163 hydrochloride; DAN-2163 hydrochloride; 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide;hydrochloride. Grades: >98%. CAS No. 81342-13-4. Molecular formula: C17H28N3O4SCl. Mole weight: 405.94. |  |
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