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| Product | Description | |
|---|---|---|
| Biricodar | Biricodar, also known as VX-710 or INCEL, is a novel compound that binds directly to P-gp. VX-710 concentrations of 0.5 to 2.5 M are sufficient to fully restore sensitivity of P-gp expressing cells to the cytotoxic action of paclitaxel and other cytotoxic drugs associated with the MDR phenotype. Synonyms: 1,7-dipyridin-3-ylheptan-4-yl (2S)-1-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate; biricodar; Incel; N-(2-oxo-2-(3,4,5-trimethoxyphenyl)acety)piperidine-2-carboxylic acid 1,7-bis(3-pyridyl)-4-heptyl ester; VX-710; VX 710; VX710; Biricodar; Incel. CAS No. 159997-94-1. Molecular formula: C34H41N3O7. Mole weight: 603.71. |  |
| Biricodar | Biricodar (VX-710) is a modulator of P-glycoprotein and MRP-1 ; shows effective chemosensitizing activity in multidrug resistant cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-710. CAS No. 159997-94-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-13574A. |  |
| Biricodar Dicitrate | Biricodar Dicitrate is the dicitrate salt form of Biricodar. Biricodar, also known as VX-710 or INCEL, is a novel compound that binds directly to P-gp. VX-710 concentrations of 0.5 to 2.5 M are sufficient to fully restore sensitivity of P-gp expressing cells to the cytotoxic action of paclitaxel and other cytotoxic drugs associated with the MDR phenotype. Synonyms: VX 710-3; (S)-1,7-di(pyridin-3-yl)heptan-4-yl 1-(2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl)piperidine-2-carboxylate dicitrate. CAS No. 174254-13-8. Molecular formula: C46H57N3O21. Mole weight: 987.96. | |
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