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| Product | Description | |
|---|---|---|
| Bizine | Lysine-specific demethylase 1 (LSD1) is an epigenetic enzyme, which can oxidatively cleave methyl groups from monomethyl and dimethyl Lys4 of histone H3. Bizine is an LSD1 inhibitor, which is a phenelzine analog that inhibits lysine-specific demethylase 1 with ki of 59 nM. It is 23-fold, 63-fold, and >100-fold selective for LSD-1 over monoamine oxidase (MAO) A, MAOB, and LSD2, respectively. Synonyms: BSM-0353. Grades: ≥95%. CAS No. 1591932-50-1. Molecular formula: C18H23N3O. Mole weight: 297.4. |  |
| Bizine hydrochloride | Bizine hydrochloride is a potent and selective histone demethylase LSD1 inhibitor. Bizine can modulate bulk histone methylation in cancer cells and protect neurons exposed to oxidative stress, suggesting potential applications in neurodegenerative disease. Uses: Potential neurodegenerative disease therapy. Synonyms: N-[4-(2-hydrazinylethyl)phenyl]-4-phenylbutanamide hydrochloride. Grades: 98%. Molecular formula: C18H23N3O.HCl. Mole weight: 333.86. | |
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