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| Product | Description | |
|---|---|---|
| bleomycin hydrolase | The molecule is a homohexamer in which the monomers have a papain-like tertiary structure (in peptidase family C1). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain. Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity. Known from bacteria as well as eukaryotic organisms. Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyses Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates. Group: Enzymes. Synonyms: aminopeptidase C (Lactococcus lactis). Enzyme Commission Number: EC 3.4.22.40. CAS No. 53096-17-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4215; bleomycin hydrolase; EC 3.4.22.40; 53096-17-6; aminopeptidase C (Lactococcus lactis). Cat No: EXWM-4215. |  |
| AUDA | AUDA is an inhibitor of soluble epoxide hydrolase with IC50 of 18 nM in mice. AUDA has been shown to demonstrate hypotensive effects, accompanied by an increase in urinary epoxide-to-diol ratios. AUDA can activate peroxisome proliferator-activated receptor α (PPARα) 3-fold, while showing no ability to affect PPARδ or PPARγ. AUDA decreases bleomycin-induced pulmonary toxicity in mice by inhibiting the p38/Smad3 pathways. Synonyms: 12-(3-Adamantan-1-yl-ureido)dodecanoic Acid; 12-[[(Tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]dodecanoic Acid; A 003564556. Grade: >98%. CAS No. 479413-70-2. Molecular formula: C23H40N2O3. Mole weight: 392.6. |  |
| H-Arg-Ala-OH | Arg-Ala inhibits angiotensin 1-converting enzyme (ACE) and yeast bleomycin hydrolase. Synonyms: Arginylalanine; Arg-Ala; L-arginyl-L-alanine; RA dipeptide; N-L-Arginyl-L-alanine; Arginine Alanine dipeptide; (S)-2-((S)-2-Amino-5-guanidinopentanamido)propanoic acid. CAS No. 40968-45-4. Molecular formula: C9H19N5O3. Mole weight: 245.28. | |
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