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| Product | Description | |
|---|---|---|
| BMPS | BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Uses: Scientific research. Group: Signaling pathways. CAS No. 55750-62-4. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-42146. |  |
| Biotin-C12-ether LBPA | Biotin-C12-ether LBPA is a biotin conjugate of ether C12 Lysobisphosphatidic acid, an ether analog of the naturally occurring, biologically active isomer of LPBA. Lysobisphosphatidic acids (LBPAs), also known as bis-(monoacylglycerol)phosphates (BMPs) are specialized lipid molecules reported to play a role in intracellular protein and lipid transport in healthy cells. Accumulation of LBPAs in intracellular, often multilamellar membranes is related to biomembrane polymorphism which may impact intracellular cholesterol transport. Synonyms: Biotin-(R,R)-2,2'-Bisdodecyl-LBPA ammonium salt. Molecular formula: C64H128N5O11PS. Mole weight: 1206.79. |  |
| LDN-214117 | LDN-214117 is an orally active ALK2 inhibitor with well-tolerated and good brain penetration. LDN-214117 has a high selectivity and low cytotoxicity for ALK2 with an IC50 value of 24 nM. LDN-214117 also is a specific bone morphogenetic proteins (BMPs) signaling inhibitor and has relatively selective inhibition for BMP6 with an IC50 value of 100 nM. LDN-214117 can be used for the research of fibrodysplasia ossificans progressiva (FOP), diffuse intrinsic pontine glioma (DIPG) [1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1627503-67-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16712. | |
| N-Succinimidyl 3-maleimidopropionate | BMPS is a nonclaevable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Synonyms: N-Succinimidyl 3-maleimidopropionate; BMPS; 2,5-Dioxopyrrolidin-1-yl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoate; 3-(Maleimido)propionic acid N-hydroxysuccinimide ester; (2,5-dioxopyrrolidin-1-yl) 3-(2,5-dioxopyrrol-1-yl)propanoate; 3-Maleimidopropionic acid N-hydroxysuccinimide ester; 3-Maleimidopropionic Acid N-Succinimidyl Ester; BMPS Crosslinker; 3-Maleimido-propionic NHS ester. Grade: 98%. CAS No. 55750-62-4. Molecular formula: C11H10N2O6. Mole weight: 266.21. | |
| PD-161570 | PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively. PD-161570 inhibits PDGF-stimulated autophosphorylation and FGF-1 receptor phosphorylation with IC50s of 450 nM and 622 nM, respectively[1][2]. PD-161570 is also a bone morphogenetic proteins (BMPs) and TGF-? signaling inhibitor[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 192705-80-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100434. | |
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