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| Product | Description | |
|---|---|---|
| BMS-754807 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| BMS-754807 | BMS-754807 is an orally bioavailable antagonist of human insulin-like growth factor type I receptor (IGF-1R) with potential antineoplastic activity. BMS-7548077 binds to IGF-1R, preventing IGF-1 ligand binding and activation of IGF-1R-mediated signaling pathways. Synonyms: BMS754807; BMS-754807; BMS 754807. Grades: 0.98. CAS No. 1001350-96-4. Molecular formula: C23H24FN9O. Mole weight: 461.505. |  |
| BMS-754807 | BMS-754807 is a potent and reversible IGF-1R / IR inhibitor ( IC 50 =1.8 and 1.7 nM, respectively; K i =<2 nM for both). BMS-754807 also shows potent activities against Met, RON, TrkA, TrkB, AurA, and AurB with IC 50 values of 6, 44, 7, 4, 9, and 25 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1001350-96-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10200. |  |
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