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| Product | Description | |
|---|---|---|
| BMS-911543 | BMS-911543 is an orally available JAK inhibitor with selectivity for JAK2. It inhibts JAK2, thereby preventing the JAK/STAT (signal transducer and activator of transcription) signaling cascade, including activation of STAT3. This may lead to an induction of tumor cell apoptosis and a decrease in cellular proliferation. Synonyms: BMS 911543. Grades: >98%. CAS No. 1271022-90-2. Molecular formula: C23H28N8O. Mole weight: 432.532. |  |
| BMS-911543 | BMS-911543 is a selective JAK2 inhibitor, with IC 50 s of 1.1 nM, less selective at JAK1, JAK3 and TYK2 ( IC 50 , 75, 360, 66 nM, respectively). Uses: Scientific research. Group: Signaling pathways. CAS No. 1271022-90-2. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15270. |  |
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