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BMY 7378 BMY 7378 is a multi-targeted inhibitor of α2C-adrenoceptor and α1D-adrenoceptor with pKi of 6.54 and 8.2, respectively, and acts as a mixed agonist and antagonist for 5-HT1A receptor with pKi of 8.3. Uses: Adrenergic alpha-antagonists. Synonyms: BMY7378; BMY-7378; 1,1-Cyclopentanediacetimide, N-(2-(4-(o-methoxyphenyl)-1-piperazinyl)ethyl)-, dihydrochloride; N-(2-(4-(o-Methoxyphenyl)-1-piperazinyl)ethyl)-1,1-cyclopentanediacetimide dihydrochloride. Grades: >98%. CAS No. 21102-95-4. Molecular formula: C22H33Cl2N3O3. Mole weight: 458.42. BOC Sciences 11
BMY 7378 BMY 7378 is a selective antagonist of α 1D -adrenoceptor (α 1D -AR). BMY 7378 binds to membranes expressing the cloned rat α 1D -AR with a >100-fold higher affinity ( K i =2 nM) than binding to either the cloned rat α 1A -AR (K i =800 nM) or the hamster α 1B -AR ( K i =600 nM). BMY 7378 is a 5-HT 1A receptor partial agonist [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 21102-95-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-100554. MedChemExpress MCE
BMY 7378 dihydrochloride ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
BMY 7378 dihydrochloride BMY 7378 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 21102-95-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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