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(S)-1-N-Boc-2-ethylpiperazine. Group: Biochemicals. Alternative Names: (2S)-2-Ethyl-1-piperazinecarboxylic acid 1,1-dimethylethyl ester. Grades: Highly Purified. CAS No. 325145-35-5. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
(S)-1-N-Boc-2-ethylpiperazine ≥96% (GC)
(S)-1-N-Boc-2-ethylpiperazine ≥96% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
1-N-Boc-4-N-benzyl-2-ethyl piperazine
1-N-Boc-4-N-benzyl-2-ethyl piperazine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: tert-Butyl 4-benzyl-2-ethylpiperazine-1-carboxylate, 502482-44-2, AGN-PC-01NRW6, SureCN6975743, CTK4J2292, MolPort-020-006-968, AKOS015960692, AB13945, AG-F-68654, AK115265, 1-N-BOC-4-N-BENZYL-2-ETHYL-PIPERAZINE, TERT-BUTYL-2-ETHYL-4-BENZYL-1-PIPERAZINECARBOXYLATE. Product Category: Heterocyclic Organic Compound. CAS No. 502482-44-2. Molecular formula: C18H28N2O2. Mole weight: 304.43. Purity: 0.96. IUPACName: tert-butyl 4-benzyl-2-ethylpiperazine-1-carboxylate. Canonical SMILES: CCC1CN(CCN1C(=O)OC(C)(C)C)CC2=CC=CC=C2. Density: 1.043g/cm³. Product ID: ACM502482442. Alfa Chemistry ISO 9001:2015 Certified.
1-Ethyl-2,3-dioxopiperazine
An impurity of Piperacillin, which is a broad-spectrum antibiotic used to treat serious, hospital-acquired infections in combination with the beta lactamase inhibitor tazobactam. Synonyms: Piperacillin Impurity E; Piperacillin EP Impurity E; Piperacillin Sodium Impurity E [EP]; Piperacillin Monohydrate Impurity E [EP]; N-Ethyl-2,3-dioxopiperazine; 1-Ethyl-2,3-piperazinedione; N-Ethylpiperazine-2,3-dione; 4-Ethyl-2,3-dioxopiperazine; 4-Ethyl-2,3-piperazinedione; 1-Ethyl-2,3-diketopiperazine; Piperacillin Related Compound E (USP); USP Piperacillin Related Compound E; Piperacillin USP Related Compound E. Grade: >95%. CAS No. 59702-31-7. Molecular formula: C6H10N2O2. Mole weight: 142.16.
7-Despropyl 7-Methyl Vardenafil
An impurity of Vardenafil. Vardenafil is a PDE5 inhibitor used for the treatment of erectile dysfunction. Synonyms: Vardenafil Impurity 3; 2-(2-Ethoxy-5-((4-ethylpiperazin-1-yl)sulfonyl)phenyl)-5,7-dimethylimidazo[5,1-f][1,2,4]triazin-4(3H)-one. Molecular formula: C21H28N6O4S. Mole weight: 460.56.
Abemaciclib
Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: LY-2835219; LY 2835219; LY2835219; Verzenio; N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine. Grade: ≥98%. CAS No. 1231929-97-7. Molecular formula: C27H32F2N8. Mole weight: 506.61.
Abemaciclib-[13C4,15N2]
Abemaciclib-[13C4,15N2] is a labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-ethylpiperazin-1-yl-2,3,5,6-13C4-1,4-15N2)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-[13C4,15N2]. Grade: ≥99% atom 13C; ≥98% atom 15N. Molecular formula: C23[13C]4H32F2N6[15N]2. Mole weight: 512.56.
Abemaciclib-[d10]
Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-(methyl-d3)-1-(propan-2-yl-d7)-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; Abemaciclib D10; N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-(methyl-d3)-1-[1-(methyl-d3)ethyl-1,2,2,2-d4]-1H-benzimidazol-6-yl]-2-pyrimidinamine; LY-2835219-d10; N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine-d10. Grade: >95%. CAS No. 2088650-71-7. Molecular formula: C27H22D10F2N8. Mole weight: 516.66.
Abemaciclib-[d5]
Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine-d5; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-d5. Grade: > 98%. CAS No. 1809251-51-1. Molecular formula: C27H27D5F2N8. Mole weight: 511.62.
Abemaciclib-[d7]
Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine-d7. Grade: > 98%. Molecular formula: C27H25D7F2N8. Mole weight: 513.64.
Abemaciclib-[d8]
Labelled Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: N-(5-((4-Ethylpiperazin-1-yl-2,2,3,3,5,5,6,6-d8)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; Abemaciclib D8; [d8]-Abemaciclib; [d8]-LY-2835219; LY-2835219-d8. Grade: ≥90%. CAS No. 2088650-53-5. Molecular formula: C27H24D8F2N8. Mole weight: 514.65.
Abemaciclib Impurity 5-[d5]
Abemaciclib Impurity 5-[d5] is a labelled impurity of Abemaciclib. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers. Synonyms: 1-[(6-bromopyridin-3-yl)methyl]-4-ethylpiperazine-d5. Grade: > 98%. CAS No. 1809251-58-8. Molecular formula: C12H13D5BrN3. Mole weight: 289.23.
abemaciclib mesylate
Abemaciclib mesylate is a CDK inhibitor with selectivity for CDK4 and CDK6. It was approved for the treatment of advanced or metastatic breast cancers. Uses: The treatment of advanced or metastatic breast cancers. Synonyms: Verzenio; LY2835219; LY 2835219; LY-2835219; UNII-KKT462Q807; Abemaciclib methanesulfonate; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate. CAS No. 1231930-82-7. Molecular formula: C28H36F2N8O3S. Mole weight: 602.706.
AEE-788
AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2), resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor-associated endothelial cell apoptosis. Synonyms: AEE 788; AEE788; 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Grade: >98%. CAS No. 497839-62-0. Molecular formula: C27H32N6. Mole weight: 440.595.
BGJ-398
BGJ398, also known as NVP-BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities. BGJ398 selectively binds to and inhibits the activities of FGFRs, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Synonyms: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-ethylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)-1-methylurea; NVPBGJ398; NVPBGJ 398; NVPBGJ-398; BGJ398; BGJ-398; BG J398; Infigratinib. Grade: 0.98. CAS No. 872511-34-7. Molecular formula: C26H31Cl2N7O3. Mole weight: 560.48.
Blonanserin
A 5-HT2 serotonin receptor and D2 dopamine receptor antagonist, used as an antipsychotic. Synonyms: 2-(4-ethylpiperazin-1-yl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine. Grade: 0.99. CAS No. 132810-10-7. Molecular formula: C23H30FN3. Mole weight: 367.512.
Gisadenafil
Gisadenafi is a potent PDE5 inhibitor (IC50 = 1.23 nM). Uses: A potent pde5 inhibitor. Synonyms: UK-369003; UK-369,003; 1-{6-ethoxy-5-[3-ethyl-6,7-dihydro-2-(2-methoxyethyl)-7-oxo-2H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-pyridylsulfonyl}-4-ethylpiperazine. Grade: ≥98%. CAS No. 334826-98-1. Molecular formula: C23H33N7O5S. Mole weight: 519.62.
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