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BPIPP BPIPP. Group: Biochemicals. Grades: Purified. CAS No. 325746-94-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
BPIPP BPIPP is a non-competitive guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor. It downregulates cAMP and cGMP synthesis, suppresses cGMP accumulation in a variety of cell lines (IC50 = 3.4 - 11.2 μM), inhibits GC-stimulated Cl- transport in vitro, and suppresses toxin-induced intestinal fluid accumulation in vivo. BPIPP may be a useful treatment of diarrhea. Uses: Potential treatment of diarrhea. Synonyms: 5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2',1':5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione. Grades: ≥99% by HPLC. CAS No. 325746-94-9. Molecular formula: C22H16BrN3O3. Mole weight: 450.28. BOC Sciences 9

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