Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| Branaplam | Branaplam Inhibitor. Uses: Scientific use. Product Category: T4641. CAS No. 1562338-42-4. |  |
| Branaplam | Branaplam (LMI070; NVS-SM1) is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC 50 of 20 nM for SMN. Branaplam inhibits human-ether-a-go-go-related gene (hERG) with an IC 50 of 6.3 μM. Branaplam elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LMI070; NVS-SM1. CAS No. 1562338-42-4. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19620. |  |
| Branaplam hydrochloride | Branaplam (LMI070; NVS-SM1) hydrochloride is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC 50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC 50 of 6.3 μM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LMI070 hydrochloride; NVS-SM1 hydrochloride. CAS No. 1562338-39-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19620A. | |
| LMI070 | LMI070, also called as NVS-SM1, is a selective, high plasma exposure and orally active modulator of SMN2 splicing which demonstrates robust activity across disease-relevant induced pluripotent stem cell (iPSc)-derived neurons. in vivo: oral administration. Synonyms: (6E)-3-(1H-pyrazol-4-yl)-6-[3-(2,2,6,6-tetramethylpiperidin-4-yl)oxy-1H-pyridazin-6-ylidene]cyclohexa-2,4-dien-1-one; UNII-P12R69543A; P12R69543A; Branaplam; Branaplam [INN]; SCHEMBL15475826; LMI-070; LMI 070; LMI070; 1562338-42-4; Phenol, 5-(1H-pyrazol-4-yl)-2-(6-((2,2,6,6-tetra. CAS No. 1562338-42-4. Molecular formula: C22H27N5O2. Mole weight: 393.48. |  |
Our database is helping our users find suppliers everyday.
