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A phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. Brassicasterol can increase accumulation of demosterol, a cholesterol precursor and substrate and inhibit cholesterol formation in HL-60 cells in a dose-dependent manner. It also inhibits the hemolytic activity of pneumolysin from S. pneumoniae. Synonyms: (3β,22E)-Ergosta-5,22-dien-3-ol; 24-Methylcholesta-5,22-dien-3β-ol; Brassicasterin; Ergosta-5,22(E)-dien-3β-ol. Grades: ≥95%. CAS No. 474-67-9. Molecular formula: C28H46O. Mole weight: 398.66.
Brassicasterol
Brassicasterol, a metabolite of Ergosterol, plays a role in the inhibitory effect on bladder carcinogenesis promotion via androgen signaling. Brassicasterol shows dual anti-infective properties against HSV-1 (IC50=1.2 μM) and Mycobacterium tuberculosis, and cardiovascular protective effect. Brassicasterol exerts an anti-cancer effect by dual-targeting AKT and androgen receptor signaling in prostate cancer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ergosta-5,22E-dien-3beta-ol; (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(E,1R,4R)-1,4,5-trimethylhex-2-enyl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Product Category: Inhibitors. Appearance: Cryst. CAS No. 474-67-9. Molecular formula: C28H46O. Mole weight: 398.66. Purity: 0.98. IUPACName: (3S,8S,9S,10R,13R,14S,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Canonical SMILES: CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C. Product ID: ACM474679-1. Alfa Chemistry ISO 9001:2015 Certified.
Brassicasterol
Brassicasterol. Group: Biochemicals. Alternative Names: (3b,22E)-Ergosta-5,22-dien-3-ol; Ergosta-5,22-dien-3b-ol; 24(R)-Methylcholesta-5,22E-dien-3b-ol. Grades: Highly Purified. CAS No. 474-67-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C28H46O. US Biological Life Sciences.
Worldwide
Brassicasterol
Brassicasterol is a metabolite of Ergosterol and has cardiovascular protective effects. Brassicasterol exerts anticancer effects in prostate cancer through dual targeting of AKT and androgen receptor signaling pathways. Brassicasterol inhibits HSV-1 ( IC 50 =1.2 μM) and Mycobacterium tuberculosis. Brassicasterol also inhibits sterol δ 24-reductase , slowing the progression of atherosclerosis. Brassicasterol is also a cerebrospinal fluid biomarker for Alzheimer's disease [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 474-67-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-113289.
Brassicasterol
from semisynthetic. Group: Fluorescence/luminescence spectroscopy.
Brassicasterol-(2,2',3,4,4',6-D6)
Brassicasterol-(2,2',3,4,4',6-D6) is derived from Brassicasterol (B676850), which is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C28H40D6O, Molecular Weight: 404.7. US Biological Life Sciences.
Worldwide
8R-Brassicasterol
8R-Brassicasterol is a by-product in the synthesis of Brassicasterol (B676850). Brassicasterol is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C28H46O. US Biological Life Sciences.
Worldwide
Beta-Sitosterol (purity>80%)
Beta-Sitosterol (purity>80%) includes β-sitosterol (≥80%), stigmasterol, campesterol and brassicasterol mainly. Beta-Sitosterol is a plant sterol. Beta-Sitosterol (purity>80%) interfere with multiple cell signaling pathways, including cell cycle, apoptosis, proliferation, survival, invasion, angiogenesis, metastasis and inflammation [1]. Uses: Scientific research. Group: Natural products. CAS No. 83-46-5. Pack Sizes: 100 mg; 1 g; 5 g. Product ID: HY-N0171.
sterol 22-desaturase
A heme-thiolate protein (P450). The enzyme, found in yeast and plants, catalyses the introduction of a double bond between the C-22 and C-23 carbons of certain sterols. In yeast the enzyme acts on ergosta-5,7,24(28)-trien-3β-ol, a step in the biosynthesis of ergosterol. The enzyme from the plant Arabidopsis thaliana acts on sitosterol and 24-epi-campesterol, producing stigmasterol and brassicasterol, respectively. Group: Enzymes. Synonyms: ERG5 (gene name); CYP710A (gene name). Enzyme Commission Number: EC 1.14.19.41. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1006; sterol 22-desaturase; EC 1.14.19.41; ERG5 (gene name); CYP710A (gene name). Cat No: EXWM-1006.
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