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| Product | Description | |
|---|---|---|
| BRD 4354 | BRD 4354 is an HDAC5 and HDAC9 inhibitor (IC50 = 0.85 and 1.88 μM, respectively) displaying >20-fold selectivity for HDAC5/9 over HDAC1/2/3. It also weakly inhibits HDAC4, HDAC6, HDAC7 and HDAC8 (IC50 values are 3.88 - 13.8 μM). Synonyms: BRD4354; BRD 4354; BRD-4354; 5-Chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-8-quinolinol. Grade: ≥98% by HPLC. CAS No. 315698-07-8. Molecular formula: C21H23ClN4O. Mole weight: 382.89. |  |
| BRD 4354 ditrifluoroacetate | BRD 4354 ditrifluoroacetate is a moderately potent HDAC5 and HDAC9 inhibitor with IC50s of 0.85 and 1.88 μM, respectively. Synonyms: 8-Quinolinol, 5-chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-, 2,2,2-trifluoroacetate (1:2); 5-Chloro-7-[(4-ethyl-1-piperazinyl)(3-pyridinyl)methyl]-8-quinolinol trifluoroacetate (1:2). CAS No. 2444837-63-0. Molecular formula: C25H25ClF6N4O5. Mole weight: 610.93. | |
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