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| Product | Description | |
|---|---|---|
| Brivanib | Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with an IC 50 of 25 nM, and has moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-540215. CAS No. 649735-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10337. |  |
| Brivanib | Brivanib is the hydrolyzed form of Brivanib alaninate, which is a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. Check for active clinical trials or closed clinical trials using this agent. Synonyms: BMS540215; BMS-540215; BMS 540215. CAS No. 649735-46-6. Molecular formula: C19H19FN4O3. Mole weight: 370.37756. |  |
| Brivanib alaninate | Brivanib alaninate is the alaninate ester of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic activity. Brivanib strongly binds to and inhibits VEGFR2, a tyrosine kinase receptor expressed almost exclusively on vascular endothelial cells; inhibition of VEGFR2 may result in inhibition of tumor angiogenesis, inhibition of tumor cell growth, and tumor regression. Check for active clinical trials or closed clinical trials using this agent. Synonyms: BMS-582664; BMS582664; BMS 582664. CAS No. 649735-63-7. Molecular formula: C22H24FN5O4. Mole weight: 441.45. | |
| Brivanib (alaninate) | Brivanib alaninate (BMS-582664) is an ATP-competitive inhibitor against VEGFR2 with an IC 50 of 25 nM; has moderate potency against VEGFR-1 and FGFR-1, but more than 240-fold against PDGFRβ [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-582664. CAS No. 649735-63-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10336. | |
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