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| Product | Description | |
|---|---|---|
| Brivudine | Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator of transcription 3), which may result in the downregulation of vascular endothelial growth factor (VEGF). BVDU has also been found to inhibit the upregulation of chemoresistance genes (Mdr1 and DHFR) during chemotherapy. Overall, the gene expression changes associated with BVDU treatment result in the decrease or prevention of chemoresistance. In addition, this agent has been shown to enhance the cytolytic activity of NK-92 natural killer cells towards a pancreatic cancer cell line in vitro. Synonyms: (E)-5-(2-Bromovinyl)-2'-deoxyuridine; (E)-5-(2-Bromovinyl)deoxyuridine; (E)-5-O-(2-bromoethenyl)-2'-deoxyuridine; 5-[(1E)-2-Bromoethenyl]-2'-deoxyuridine; 5-[(E)-2-Bromoethenyl]-2'-deoxyuridine; BVDU; Brivudin; Bromovinyldeoxyuridine; Helpin. Grades: ≥98% by HPLC. CAS No. 69304-47-8. Molecular formula: C11H13BrN2O5. Mole weight: 333.14. |  |
| Brivudine | Brivudine. CAS No. 69304-47-8. Product ID: 3-02760. Molecular formula: C11H13BrN2O5. Mole weight: 333.14. Purity: 0.98. |  |
| Brivudine | Brivudine is a nucloside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-Herpes medication. Group: Biochemicals. Grades: Highly Purified. CAS No. 69304-47-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C11H13BrN2O5, Molecular Weight: 333.14. US Biological Life Sciences. |  Worldwide |
| Brivudine | Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Bromovinyldeoxyuridine; BVDU. CAS No. 69304-47-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-13578. |  |
| Brivudine 5'-Diphosphate Tristriethyl Ammonium Salt | Brivudine 5'-Diphosphate Tristriethyl Ammonium Salt is derived from Brivudine, which is a nucleoside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-Herpes medication. Molecular formula: C11H15BrN2O11P2 C6H15N. Mole weight: 493.10. | |
| Brivudine 5'-Monophosphate | Brivudine 5'-Monophosphate is a hetero-dinucleotide that acts as an anti-tumor agent against AH13 rat sarcoma cells. A nucleotide derivative which is an active species of the novel anticancer drug, NB 1011. Anti-viral. Synonyms: BVDU 5'-Monophosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine 5'-Monophosphate; 5-[(1E)-2-Bromoethenyl]-2'-deoxy-5'-uridylic Acid; (E)-5-(2-bromoethenyl)-2'-deoxy-5'-uridylic Acid. CAS No. 80860-82-8. Molecular formula: C11H14BrN2O8P. Mole weight: 413.12. | |
| Brivudine 5'-Triphosphate Ammonium | Brivudine 5'-Triphosphate Ammonium Salt is derived from Brivudine, which is a nucleoside analog which causes induction of neuronal differentiation in human reporter cell lines and adult stem cells. Anti-herpes medication. Synonyms: 5-(2-Bromovinyl)-2'-deoxyuridine-5'-triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromoethenyl]-2,4-dioxopyrimidin-1-yl]-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-(2-bromoethenyl)-2'-deoxy-, (E)-; BVdUTP; BV(5)Dutp; Bvdu-tp; SCHEMBL442341; SCHEMBL442343; CHEMBL4594370; (E)-5-(2-Bromovinyl)-dUTP; Brivudine 5'-Triphosphate Ammonium; E-5-Bromovinyl-2'-deoxyuridine triphosphate; (E)-5-(2-Bromovinyl)-2'-deoxyuridine triphosphate; (e)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate; Uridine 5'-(tetrahydrogen triphosphate), 5-[(1E)-2-bromoethenyl]-2'-deoxy-; ((2R,3S,5R)-5-(5-((E)-2-Bromovinyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; [[(2R,3S,5R)-5-[5-[(E)-2-bromovinyl]-2,4-dioxo-pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate. Molecular formula: C11H16BrN2O14P3. Mole weight: 573.08. | |
| Brivudine Impurity 11 | Brivudine Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1053650-23-9. Molecular formula: C25H20Br2Cl2N2O7. Mole weight: 691.15. Catalog: APB1053650239. |  |
| Brivudine Impurity 16 | Brivudine Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113890-35-0. Molecular formula: C5H10O4. Mole weight: 134.13. Catalog: APB113890350. | |
| Brivudine Impurity 17 | Brivudine Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122776-03-8. Molecular formula: C10H16ClNO3. Mole weight: 233.69. Catalog: APB122776038. | |
| Brivudine Impurity 19 | Brivudine Impurity 19. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113890-38-3. Molecular formula: C5H10O4. Mole weight: 134.13. Catalog: APB113890383. | |
| Brivudine Impurity 22 | Brivudine Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18546-37-7. Molecular formula: C5H10O4. Mole weight: 134.13. Catalog: APB18546377. | |
| Brivudine Impurity ((E)-5-(2-Bromovinyl)uracil ) | Brivudine Impurity ((E)-5-(2-Bromovinyl)uracil) is an impurity commonly found in Brivudine. Brivudine is an antiviral drug used to treat herpes zoster (shingles) and genital herpes. Synonyms: 5-[(1E)-2-Bromoethenyl]-2,4(1H,3H)-pyrimidinedione. Grades: > 95%. CAS No. 69304-49-0. Molecular formula: C6H5BrN2O2. Mole weight: 217.02. | |
| 5-(E)-(2-Bromovinyl)-2'-deoxyuridine | 5-(E)-(2-Bromovinyl)-2'-deoxyuridine. Group: Biochemicals. Alternative Names: Brivudine. Grades: Highly Purified. CAS No. 69304-47-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C11H13BrN2O5. US Biological Life Sciences. | Worldwide |
| 5'-O-(Dimethoxytrityl)-5-(1-propynyl)-2'-deoxyuridine | 5'-O-(Dimethoxytrityl)-5-(1-propynyl)-2'-deoxyuridine is an indispensable compound within the biomedical domain, serving as a foundational constituent in the research and development of antiviral medications like Brivudine. Synonyms: 2'-Deoxy-5'-O-[(2,3-dimethoxyphenyl)(diphenyl)methyl]-5-prop-1-yn-1-yluridine; 644962-74-3; 1-[(2R,4S,5R)-5-[[(2,3-dimethoxyphenyl)-diphenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-5-prop-1-ynylpyrimidine-2,4-dione; DTXSID50722442. Grades: ≥ 95%. CAS No. 644962-74-3. Molecular formula: C33H32N2O7. Mole weight: 568.62. | |
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