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BRL-37344 BRL-37344 (Fosigotifator (THAM sodium)) is a specific β3-adrenergic receptor agonist. BRL-37344 treatment significantly lowers the body weight of obese mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 90730-96-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101325A. MedChemExpress MCE
BRL-37344 sodium BRL37344 is a selective β3-adrenergic receptor agonist originated by GlaxoSmithKline. Ki value is 287nM for β3 receptor, 1750nM for β1 receptor and 1120nM for β2 receptor. BRL37344 can decrease nerve-evoked contractions in human detrusor smooth muscle isolated strips, it can also stimulate fuel oxidation by soleus muscle in vitro. BRL37344 increases glucose transport into L6 myocytes through a mechanism different from that of insulin. But preclinical for Diabetes mellitus was discontinued. Uses: Diabetes mellitus. Synonyms: BRL-37344 sodium; BRL 37344 sodium; BRL37344 sodium; sodium; 2- [4- [ (2R) -2- [ [ (2R) -2- (3-chlorophenyl) -2-hydroxyethyl] amino] propyl] phenoxy] acetate. Grades: 98 %. CAS No. 127299-93-8. Molecular formula: C19H21ClNNaO4. Mole weight: 385.82. BOC Sciences 10

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