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| Product | Description | |
|---|---|---|
| Bromoenol lactone | ?98% (TLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Bromoenol lactone | BEL is a selective, potent, irreversible, mechanism-based inhibitor of myocardial cytosolic calcium-independent phospholipase A2 (iPLA2) with a Ki value of 180 nM. BEL induces the proteolysis of procaspase-9 and procaspase-3 and increases cleavage of poly (ADP-ribose) polymerase. BEL also inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM and is an effective enzyme-activated irreversible inhibitor of chymotrypsin Ki of 636 nM. Long term treatment with BEL increased annexin-V binding to the cell surface and nuclear DNA damage. Synonyms: BEL; Haloenol lactone; HELSS. Grades: ≥95%. CAS No. 88070-98-8. Molecular formula: C16H13BrO2. Mole weight: 317.2. |  |
| Bromoenol lactone | Bromoenol lactone ((6E)-Bromoenol lactone) is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A 2 (iPLA 2 β) with an IC 50 value of approximately 7 μM, which inhibits antigen-stimulated mast cell exocytosis without blocking Ca 2+ influx [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (6E)-Bromoenol lactone. CAS No. 88070-98-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107411. |  |
| (R)-Bromoenol lactone | (R)-Bromoenol lactone is an irreversible inhibitor of iPLA2&gamma. Synonyms: (R)-BEL; (3R)-6-Ethylidene-3-(naphthalen-1-yl)oxan-2-one; 6E-(bromoethylene)tetrahydro-3R-(1-naphthalenyl)-2H-pyran-2-one. Grades: ≥98%. CAS No. 478288-90-3. Molecular formula: C16H13BrO2. Mole weight: 317.2. | |
| (S)-Bromoenol lactone | (S)-Bromoenol lactone is an irreversible inhibitor of iPLA2&gamma. Synonyms: (S)-BEL; 6E-(bromoethylene)tetrahydro-3S-(1-naphthalenyl)-2H-pyran-2-one. Grades: ≥98%. CAS No. 478288-94-7. Molecular formula: C16H13BrO2. Mole weight: 317.2. | |
| (R)-Bel | (R)-Bel. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (R)-BEL;(R)-Bromoenol lactone. Product Category: Heterocyclic Organic Compound. Appearance: Solution in methyl acetate. CAS No. 478288-90-3. Molecular formula: C16H13BrO2. Mole weight: 317.18. Product ID: ACM478288903. Alfa Chemistry ISO 9001:2015 Certified. Categories: R. Belle Colver. |  |
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