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| Product | Description | |
|---|---|---|
| Bruceine A | Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.); are potential candidates for the treatment of canine babesiosis.IC50 value:Target:Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazene aceturate and killed the parasites within 24 hr at a concentration of 25 nM. Oral administration of bruceine A at a dosage of 6.4 mg/kg/day for 5 days resulted in no clinical findings in a dog with normal ranges of hematological and biochemical values in the blood. Three dogs were infected with B. gibsoni and two of them were treated with bruceine A at a dosage of 6.4 mg/kg/day for 6 days from day 5 post-infection. Group: Inhibitors. CAS No. 25514-31-2. Molecular formula: C26H34O11. Mole weight: 522.54. Appearance: Powder. Purity: 0.98. Canonical SMILES: CC1=C (C (=O)CC2 (C1CC3C45C2C (C (C (C4C (C (=O)O3)OC (=O)CC (C)C) (OC5)C (=O)OC)O)O)C)O. Catalog: ACM25514312. |  |
| Bruceine D | Bruceine D is a Notch inhibitor with anti-cancer activity and induces apoptosis in several human cancer cells. Bruceine D is an effective botanical insect antifeedant with outstanding systemic properties, causing potent pest growth inhibitory activity. Bruceine D has strong anthelmintic activity against D. intermedius with an EC50 value of 0.57 mg/L. Group: Inhibitors. CAS No. 21499-66-1. Molecular formula: C20H26O9. Mole weight: 410.4. Appearance: Powder. Purity: 0.98. Canonical SMILES: CC1=CC (=O)C (C2 (C1CC3C45C2C (C (C (C4 (C (C (=O)O3)O)O) (OC5)C)O)O)C)O. Catalog: ACM21499661. | |
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