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| Product | Description | |
|---|---|---|
| Bryostatin 1 | Bryostatin 1, a structurally unique macrolactone marine natural product, is a protein kinase C (PKC) activator that binds with high affinity (Ki = 1.35 nM). Bryostatin 1 fails to mimic many effects caused by PMA and actually blocks some PMA-induced response in a variety of cells and tissues. Animal tests have shown bryostatin 1 may alleviate brain damage after a stroke. Uses: Adjuvants, immunologic. Synonyms: Bryostatin-1; Bryostatin1; NSC-339555; NSC 339555; NSC339555; AC1L8WCW. Grades: ≥99%. CAS No. 83314-01-6. Molecular formula: C47H68O17. Mole weight: 905.04. |  |
| Bryostatin 1 | Bryostatin 1. Group: Biochemicals. Grades: Purified. CAS No. 83314-01-6. Pack Sizes: 10ug. US Biological Life Sciences. |  Worldwide |
| Bryostatin 1 | Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a potent and central nervous system (CNS)-permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein with Kis of 8.07 nM and 0.45 nM, respectively. Bryostatin 1 has anti-cancer, anti-inflammatory, neuroprotective, anti-HIV-1 infection properties. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BRYOSTATIN 1;BRYO 1;2,4-Octadienoic acid, (1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(acetyloxy)-1,11,21-trihydroxy-17-(1R)-1-hydroxyethyl-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo21.3.1.13,7.111,15nonacos-8-en;BRYOSTATIN;bryostatin1,0;(26R)-Bryostatin 1;NSC-339555;(1S,3S,5Z,7R,8E,11S,12S,13E,15S,17R,21R,23R,25S)-25-(Acetyloxy)-1,11,21-trihydroxy-17-[(1R)-1-hydroxyethyl]-5,13-bis(2-methoxy-2-oxoethylidene)-10,10,26,26-tetramethyl-19-oxo-18,27,28,29-tetraoxatetracyclo[21.3.1.13,7.111,15]nonacos-8-en-12-yl2,4-octadienoicacidester. Product Category: Inhibitors. Appearance: solid. CAS No. 83314-01-6. Molecular formula: C47H68O17. Mole weight: 905.03. Purity: ≥99.0%. Product ID: ACM83314016. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Bryostatin 1 (NSC 339555, B705008K112, BRN 4349157) | Bryostatin 1 binds to and activates protein kinase C, but its biological effects differ greatly from those induced by other protein kinase C activators. Bryostatin 1 fails to mimic many effects caused by PMA and actually blocks some PMA-induced response in a variety of cells and tissues. Group: Biochemicals. Grades: Highly Purified. CAS No. 83314-01-6. Pack Sizes: 10ug, 25ug. US Biological Life Sciences. | Worldwide |
| Bryostatin 2 | Bryostatin 2, an analog of Bryostatin 1, is an activator of PKC (protein kinase C) with anti-tumor properties. Bryostatin 2 inhibits DNA synthesis at 100 nM in SH-SY5Y human neuroblastoma cells. Synonyms: Bryostatin-2; Bryostatin2; Deacetyl Bryostatin 1; Deacetyl Bryostatin-1; NSC 339554; NSC339554; NSC-339554. Grades: ≥95% by HPLC. CAS No. 87745-28-6. Molecular formula: C45H66O16. Mole weight: 862.99. | |
| Bryostatin 2 | Bryostatin 2. Group: Biochemicals. Grades: Purified. CAS No. 87745-28-6. Pack Sizes: 10ug. US Biological Life Sciences. | Worldwide |
| Bryostatin 3 | Bryostatin 3. Group: Biochemicals. Grades: Purified. CAS No. 143370-84-7. Pack Sizes: 10ug. US Biological Life Sciences. | Worldwide |
| Bryostatin 3 | Bryostatin 3 has been found to be a potent protein kinase C activator and could probably be useful in studies of emerging cancers. Synonyms: Bryostatin 3; 143370-84-7; (4S, 5S, 7E, 9R, 11Z, 13S, 15S, 17S, 19R, 21R, 25R, 27R, 27aS)-17-(Acetyloxy)-4, 5, 6, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20,21,22,23,25,26,27,27a-docosahydro-5,15,21-trihydroxy-25-[(1R)-1-hydroxyethyl]-11-(2-methoxy-2-oxoethylidene)-6,6,16,16-tetramethyl-2,23-dioxo-5,27:9,13:15,19-triepoxy-2H-furo[2,3-e]oxacyclohexacosin-4-yl-(2E,4E)-2,4-octadienoic acid ester. Grades: ≥95% by HPLC. CAS No. 143370-84-7. Molecular formula: C46H64O17. Mole weight: 888.99. | |
| 1-(Aminomethyl)-2-methyl-2-(1-methylethyl)-cyclopropanemethanol | 1-(Aminomethyl)-2-methyl-2-(1-methylethyl)-cyclopropanemethanol can be obtained from 3-Methyl-2-butanone (M294155) which is a reagent used in the synthesis of bryostatin analogs used as a cancer chemotherapeutic. Also used in the preparation of esterase-labile protection groups for phosphodiesters. Group: Biochemicals. Grades: Highly Purified. CAS No. 1339616-57-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H19NO, Molecular Weight: 157.25. US Biological Life Sciences. | Worldwide |
| 2,4-Dideoxy-6-O-(phenylmethyl)-L-threo-hexonic Acid tert-Butyl Ester | 2,4-Dideoxy-6-O-(phenylmethyl)-L-threo-hexonic Acid tert-Butyl Ester is used in the preparation of (3R,5R)-Rosuvastatin (R700510), phorboxazole B and bryostatin 2. Group: Biochemicals. Alternative Names: 2,4-Dideoxy-6-O-(phenylmethyl)-L-threo-hexonic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 215876-09-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 4-Chloro-1-butanol (Technical Grade) | 4-Chloro-1-butanol is a reagent used in the preparation of pharmaceutical compounds such as canthine analogues for their activity against HeLa cervical cells. Also used in the preparation of novel and highly potent Bryostatin, another anti-cancer agent. Group: Biochemicals. Alternative Names: 1-Chloro-4-butanol; 2-(2-Chloroethyl)ethanol; 4-Chloro-1-butanol; 4-Chloro-1-hydroxybutane; 4-Chlorobutanol; NSC 10810; Tetramethylene chlorohydrin; ω-Chlorobutanol. Grades: Purified. CAS No. 928-51-8. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| (5R)-5-Hydroxy-3-oxo-6-(benzyloxy)-hexanoic Acid tert-Butyl Ester | (5R)-5-Hydroxy-3-oxo-6-(benzyloxy)-hexanoic Acid tert-Butyl Ester is used in the preparation of antifungal macrolide antibiotic (+)-Roxaticin, Phorboxazole B and Bryostatin 2. Group: Biochemicals. Alternative Names: (5R)-5-Hydroxy-3-oxo-6-(phenylmethoxy)-hexanoic Acid 1,1-Dimethylethyl Ester. Grades: Highly Purified. CAS No. 147849-63-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| NPG Glycol | NPG Glycol is used in the synthesis of tetraphenylporphyrins. Also used in the synthesis of Bryostatin 2, a protein kinase modulator. Group: Biochemicals. Alternative Names: 2,2-Dimethyl-1,3-propanediol; Neoppentylglycol; 1,3-Dihydroxy-2,2-dimethylpropane; 2, 2-Bis (hydroxymethyl) propane; 2,2-Dimethyl-1,3-dihydroxypropane; 2,2-Dimethyl-1,3-propanediol; 2,2-Dimethyl-1,3-propylene Glycol; 2,2-Dimethylolpropane; 2,2-Dimethylpropan-1,3-diol; 2,2-Dimethylpropanediol Monoacrylate Monomethacrylate; 2,2-Dimethyltrimethylene Glycol; Dimethylolpropane; Hydroxypivalyl Acohol; NSC 55836; NSC 6366; Neopentanediol; Neopentyl Glycol; Neopentylene Glycol; Nexcoat 600. Grades: Highly Purified. CAS No. 126-30-7. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
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