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Buserelin is a Gonadotropin-releasing hormone agonist (GnRH agonist). The drug's effects are dependent on the frequency and time course of administration. GnRH is released in a pulsatile fashion in the postpubertal adult. Initial interaction of any GnRH agonist, such as buserelin, with the GnRH receptor induces release of FSH and LH by gonadotrophes. Synonyms: (Des-Gly10,D-Ser(tBu)6,Pro-NHEt9)-LHRH; Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-L-proline ethylamide; Bigonist; HOE-766; HOE766; HOE 766; Profact; Receptal; Suprecur; Suprefact; Tiloryth; Hoe-766 MP; D-Ser(tbu(sup 6))-LH-RH-(1-9)-nonapeptide ethylamide; (D-Ser(tbu)(sup 6)-EA(sup 10))-luteinizing hormone-releasing hormone. Grades: >98%. CAS No. 57982-77-1. Molecular formula: C60H86N16O13. Mole weight: 1239.42.
Buserelin
Buserelin. Uses: For analytical and research use. Group: Impurity standards. CAS No. 57982-77-1. Molecular Formula: C60H86N16O13. Mole Weight: 1239.45. Catalog: APB57982771.
Buserelin Acetate
Buserelin acetate is an imputity of Buserelin, which is a synthetic analogue of gonadotropin-releasing hormone (GnRH). It functions via binding to GnRH receptors. Buserelin is primarily used for the treatment of prostate cancer and endometriosis. Uses: Fertility agents, female. Synonyms: H-Pyr-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt.CH3CO2H; L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-O-tert-butyl-D-seryl-L-leucyl-L-arginyl-L-proline ethylamide acetic acid; 6-[O-(1,1-Dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-1-9-luteinizing Hormone-releasing Factor Acetate; Estomal; Suprafact; Suprecur; Receptal; Supremon. Grades: ≥95%. CAS No. 68630-75-1. Molecular formula: C62H90N16O15. Mole weight: 1299.48.
Buserelin Acetate
Gondadotropin-releasing hormone agonist, used to treat hormone-responsive cancers such as prostate and breast cancer. Synthetic nonapeptide agonist analog of LH-RH. Antineolpastic (hormonal). Group: Biochemicals. Alternative Names: 6-[O-(1,1-Dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-1-9-luteinizing Hormone-releasing Factor Monoacetate; Estomal; Suprafact; Suprecur; Supremon. Grades: Highly Purified. CAS No. 68630-75-1. Pack Sizes: 10mg. Molecular Formula: C??H??N??O??, Molecular Weight: 1299.48. US Biological Life Sciences.
Worldwide
Buserelin EP Impurity A
Buserelin EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1872434-99-5. Molecular Formula: C60H86N16O13. Mole Weight: 1239.45. Catalog: APB1872434995.
Buserelin EP Impurity B
Buserelin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1926163-21-4. Molecular Formula: C60H86N16O13. Mole Weight: 1239.45. Catalog: APB1926163214.
Buserelin EP Impurity C
Buserelin EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 70280-55-6. Molecular Formula: C49H74N12O10. Mole Weight: 991.2. Catalog: APB70280556.
Buserelin EP Impurity D
Buserelin EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 88699-82-5. Molecular Formula: C60H86N16O13. Mole Weight: 1239.45. Catalog: APB88699825.
Buserelin EP Impurity E
Buserelin EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1926163-20-3. Molecular Formula: C60H86N16O13. Mole Weight: 1239.45. Catalog: APB1926163203.
Buserelin EP Impurity F
Buserelin EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C63H91N17O15. Mole Weight: 1326.53. Catalog: APB06953.
Buserelin EP Impurity G
Buserelin EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C65H93N17O14. Mole Weight: 1336.56. Catalog: APB06954.
Buserelin-NHNH2 trifluoroacetate salt
Buserelin, sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis. Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH. It is a long-acting agent that, after an initial increase in sex hormone levels by about 95% in both sexes, decreases the level of circulating gonadotropins and sex hormones. Buserelin can reduce tumor growth in a DMBA-induced rat model of mammary cancer. The medication is one of only two medically used GnRH analogues that are available as nasal sprays, the other being nafarelin. Buserelin is available as a generic medication. Grades: ≥95%. Molecular formula: C58H83N17O13·xCF3COOH. Mole weight: 1226.39.
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