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| Product | Description | |
|---|---|---|
| BX 471 | BX 471. Group: Biochemicals. Grades: Purified. CAS No. 217645-70-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| BX 471 | BX 471 is a selective CCR1 antagonist. Synonyms: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea; BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. |  |
| BX-471 | BX-471, also known as ZK-811752, is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). BX-471 exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4. BX-471 was developed Berlex and its parent company, Schering AG. BX-471 is the lead in a series of non-peptide chemokine receptor 1 (CCR1) antagonists, for the potential treatment of autoimmune diseases, in particular multiple sclerosis (MS). In March 2000, BX-471 was undergoing phase I trials for the potential treatment of autoimmune diseases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BX471; BX 471; BX-471; ZK811752; ZK 811752; ZK-811752. Product Category: Antagonists. Appearance: Solid powder. CAS No. 217645-70-0. Molecular formula: C21H24ClFN4O3. Mole weight: 434.89. Purity: >98%. IUPACName: (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea. Canonical SMILES: C[C@H]1N(C(COC2=CC=C(Cl)C=C2NC(N)=O)=O)CCN(CC3=CC=C(F)C=C3)C1. Product ID: ACM217645700. Alfa Chemistry ISO 9001:2015 Certified. Categories: Bx41 (New York City bus). |  |
| BX471 hydrochloride | BX471 hydrochloride is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1). Synonyms: BX-471 hydrochloride; BX 471 hydrochloride; (R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea hydrochloride. CAS No. 288262-96-4. Molecular formula: C21H25Cl2FN4O3. Mole weight: 471.35. | |
| BX912 | BX-912 is a selective inhibitor of 3-Phosphoinositide-dependent Kinase-1 (PDK1) with IC50 of 12 nM; >10 fold selectivity over PKA, PKC, C-Kit, EGFR etc. Synonyms: BX912; BX 912; BX-912. Grades: 0.98. CAS No. 702674-56-4. Molecular formula: C20H23BrN8O. Mole weight: 471.363. | |
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