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| Product | Description | |
|---|---|---|
| BX 513 hydrochloride | BX 513 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1216540-18-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| BX 513 hydrochloride | BX 513 hydrochloride is a selective CCR1 receptor antagonist (Ki = 0.04, > 10, > 10 and > 10 nM for CCR1, CCR5, CXCR2 and CXCR4 receptors, respectively), and also acts as a US28 agonist. It inhibits MIP-1α-induced intracellular calcium mobilization (IC50 = 2.5 μM). Synonyms: BX-513 hydrochloride; BX513 hydrochloride; 1-Piperidinepentanenitrile, 4-(4-chlorophenyl)-4-hydroxy-α,α-diphenyl-, hydrochloride (1:1); 4-(4-Chlorophenyl)-4-hydroxy-α,α-diphenyl-1-piperidinepentanenitrile hydrochloride; VUF 2274 hydrochloride; 5-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidyl]-2,2-diphenyl-pentanenitrile hydrochloride. Grades: ≥99% by HPLC. CAS No. 1216540-18-9. Molecular formula: C28H29ClN2O.HCl. Mole weight: 481.46. |  |
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