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| Product | Description | |
|---|---|---|
| Cabozantinib impurity 59 | Cabozantinib impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-ethoxy-3-oxopropanoic acid. CAS No. 1071-46-1. Molecular formula: C5H8O4. Mole weight: 132.11. Catalog: APB1071461. |  |
| Cabozantinib Des-O-fluoroaniline | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1-((4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylic acid; Cabozantinib Impurity 03. CAS No. 849217-77-2. Molecular formula: C22H20N2O6. Mole weight: 408.40. |  |
| Cabozantinib N-oxide | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 4-(4-(1-((4-fluorophenyl)carbamoyl)cyclopropane-1-carboxamido)phenoxy)-6,7-dimethoxyquinoline 1-oxide; 1,1-Cyclopropanedicarboxamide, N-(4-((6,7-dimethoxy-1-oxido-4-quinolinyl)oxy)phenyl)-N'-(4-fluorophenyl)-; Cabozantinib Impurity 04. CAS No. 1621681-63-7. Molecular formula: C28H24FN3O6. Mole weight: 517.51. | |
| N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)-N-phenylcyclopropane-1,1-dicarboxamide | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-N'-phenyl-; Cabozantinib Impurity 02. CAS No. 849221-94-9. Molecular formula: C28H25N3O5. Mole weight: 483.52. | |
| N-(4-fluorophenyl)-N-(4-((6-hydroxy-7-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N-(4-fluorophenyl)-N'-[4-[(7-hydroxy-6-methoxy-4-quinolinyl)oxy]phenyl]-; Cabozantinib Impurity 06. CAS No. 1628530-42-6. Molecular formula: C27H22FN3O5. Mole weight: 487.48. | |
| N-(4-fluorophenyl)-N-(4-((7-hydroxy-6-methoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N-(4-fluorophenyl)-N'-(4-((6-hydroxy-7-methoxy-4-quinolinyl)oxy)phenyl)-; Dimethyl cabozantinib; Cabozantinib Impurity 05. Grades: 99% by HPLC. CAS No. 1628530-47-1. Molecular formula: C27H22FN3O5. Mole weight: 487.48. | |
| N,N'-bis(4-((6,7-dimethoxyquinolin-4-yl)oxy)phenyl)cyclopropane-1,1-dicarboxamide | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: 1,1-Cyclopropanedicarboxamide, N,N'-bis(4-((6,7-dimethoxy-4-quinolinyl)oxy)phenyl)-; Cabozantinib Impurity 01. CAS No. 2439164-91-5. Molecular formula: C39H34N4O8. Mole weight: 686.72. | |
| N,N'-bis(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | It is an impurity of Cabozantinib. Cabozantinib is a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: Cabozantinib Impurity EXA; 1,1-Cyclopropanedicarboxamide, N,N'-bis(4-fluorophenyl)-; Cabozantinib Impurity 06. CAS No. 1431468-36-8. Molecular formula: C17H14F2N2O2. Mole weight: 316.30. | |
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