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| Product | Description | |
|---|---|---|
| Cabozantinib S-malate | Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. Synonyms: Cabozantinib malate; cabozantinib (S)-malate; Cabometyx; 1-N-[4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-1-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (2S)-2-hydroxybutanedioic acid. Grades: >98%. CAS No. 1140909-48-3. Molecular formula: C28H24FN3O5.C4H6O5. Mole weight: 635.59. |  |
| Cabozantinib S-malate | Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2 , c-Met , Kit , Axl and Flt3 with IC 50 s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: XL184 S-malate; BMS-907351 S-malate. CAS No. 1140909-48-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12044. |  |
| Cabozantinib L-Malate Salt | Cabozantinib is a small molecule C-Met modulator. Cabozantinib acts as a potent multitargeted VEGFR2, Met, FLT3, Tie2, Kit and Ret inhibitor with IC50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nM for VEGFR2, Met, FLT3, Tie2 and Kit, respectively. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis. Group: Biochemicals. Alternative Names: N- [4- [ (6, 7-Dimethoxy-4-quinolinyl) oxy] phenyl] -N- (4-fluorophenyl) -1, 1-cyclopropane dicarboxamide (2S)-2-Hydroxybutanedioic Acid; Cabozantinib S-Malate; BMS-907351; XL-184; Cometriq. Grades: Highly Purified. CAS No. 849217-68-1. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. |  Worldwide |
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