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Cafestol is a natural bioactive substance isolated from the unsaponifiable fraction of petroleum ether extract of coffee beans, it acts as a GST (glutathione S-transferase) inducer and exhibits chemoprotective activity. Dietary cafestol does increase total cholesterol and triglycerides in ApoE3Leiden mice, an effect which is associated with selective activation of farnesoid X receptors and pregnane X receptors. Synonyms: cafestol; 469-83-0; cafesterol; CCRIS 1518; AC465T6Q6W; CHEBI:3291; (3bS,5aS,7R,8R,10aR,10bS)-7-(hydroxymethyl)-10b-methyl-3b,4,5,6,7,8,9,10,10a,10b,11,12-dodecahydro-5a,8-methanocyclohepta[5,6]naphtho[2,1-b]furan-7-ol. Grades: ≥98%. CAS No. 469-83-0. Molecular formula: C20H28O3. Mole weight: 316.4.
Cafestol
Cafestol is an orally active diterpenoid and an inhibitor of ERK2. Cafestol has elevated blood lipids, anti-inflammatory, anti-angiogenic and anti-diabetic activities. In addition, Cafestol induces tumor cell apoptosis and autophagy , which can be used in the study of cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 469-83-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N6257.
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