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Cambinol Cambinol is a cell-permeable inhibitor of SIRT1 and SIRT2 inhibitor with IC50 values of 56 μM and 59 μM, respectively. Synonyms: 2,3-dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1H)-pyrimidinone; Cambinol; NSC 112546; SIRT1 Inhibitor II; SIRT2 Inhibitor VI; SIRT 1/2 inhibitor IV; NSC112546; NSC-112546; NSC 112546. CAS No. 14513-15-6. Molecular formula: C21H16N2O2S. Mole weight: 360.43. BOC Sciences 10
Cambinol Cambinol is a SIRT1 and SIRT2 inhibitor with IC50 values of 56 μM and 59 μM, respectively. Cambinol is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Uses: Designed for use in research and industrial production. Additional or Alternative Names: cambinol, NSC112546, NSC-112546, SIRT1/2 Inhibitor IV, Cambinol, 14513-15-6, 5-(2-Hydroxy-naphthalen-1-ylmethyl)-6-phenyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one, AC1MMYEF, NCIStruc1_001428, NCIStruc2_001159, SureCN3332758, CHEMBL491960, CTK8G3107, HMS3261K21, CCG-37240, DNC009417, NCGC00014121, NCI112546, AKOS002364304, AG-D-88787, CCG-221684. Product Category: Inhibitors. CAS No. 14513-15-6. Molecular formula: C21H16N2O2S. Mole weight: 360.43. Purity: 0.96. IUPACName: 5-[(2-hydroxynaphthalen-1-yl)methyl]-6-phenyl-2-sulfanylidene-1H-pyrimidin-4-one. Density: 1.41g/cm³. Product ID: ACM14513156. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Campanology. Alfa Chemistry.

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