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Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2 , shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Camostat mesilate; FOY305; FOY-S980. CAS No. 59721-29-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13512.
Camostat Mesylate
Camostat (INN) or FOY-305 is a serine protease inhibitor. Serine protease enzymes have a variety of functions in the body, and so camostat has a diverse range of uses. It is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or kidney disease orpancreatitis. Uses: Trypsin inhibitors. Synonyms: 4-(2-(2-(dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate methanesulfonate; Camostat Mesilate; Camostat Mesylate; FOY 305; FOY-305; FOY305. Grades: >98%. CAS No. 59721-29-8. Molecular formula: C20H22N4O5.CH4O3S. Mole weight: 494.52.
Camostat Mesylate
Orally active, non-peptide proteolitic enzyme inhibitor with anti-trypsin and anti-plasmin activities, related structurally to gabexate. Protease inhibitor. Camostat mesilate is a serine protease inhibitor that inhibits plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis. It reduces weight gain and improves metabolism in obese rodent models. It is in clinical use (in Japan) for pancreatitis. Camostat has been found to inhibit influenza virus replication in human tracheal epithelial cells and is also a direct prostasin inhibitor which may be useful in reducing sodium transport in cystic fibrosis. Additionally it has been shown to reduce infection of Calu-3 lung cells by SARS-CoV-2 (the coronavirus responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming. Group: Biochemicals. Alternative Names: 4- [ [4- [ (Aminoiminomethyl) amino] benzoyl] oxy] benzeneacetic Acid 2-(Dimethylamino)-2-oxoethyl Ester Methanesulfonate; FOY 305; FOY-S 980; Foipan. Grades: Highly Purified. CAS No. 59721-29-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
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Camostat Mesylate-D6
Camostat mesylate-D6 is a labelled analogue of Camostat mesylate (C150300). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C21H20D6N4O8S, Molecular Weight: 500.56. US Biological Life Sciences.
2-(Dimethylamino)-2-oxoethyl 4- (4-guanidinobenzoyloxy) phenylacetate. Group: Biochemicals. Alternative Names: Camostat. Grades: Highly Purified. CAS No. 59721-28-7. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C20H22N4O5. US Biological Life Sciences.
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FOY 251
A metabolite of Camostat. It is a pollen protease inhibitor for prevention and control of allergy. Group: Biochemicals. Alternative Names: 4-[[4-[ (Aminoiminomethyl) amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate. Grades: Highly Purified. CAS No. 71079-09-9. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 409.41. US Biological Life Sciences.
Worldwide
FOY 251
FOY 251 is a metabolite of camostat mesilate, and a proteinase inhibitor. Synonyms: FOY251; FOY-251; 4-(4-Guanidinobenzoyloxy)phenylacetic acid; 4-GBCE (methanesulfonate). CAS No. 71079-09-9. Molecular formula: C17H19N3O7S. Mole weight: 409.4.
Ono 3403, a derivative of camostat mesilate and has a higher protease-inhibitory activity, is a synthetic serine protease inhibitor that inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock. Synonyms: (4-carbamimidoylphenyl) 4-[(E)-3-[(2-ethoxy-2-oxoethyl)-prop-2-enylamino]-2-methyl-3-oxoprop-1-enyl]benzoate;methanesulfonic acid; ethyl N-allyl-N- (2-methyl-3- (4- (4-amidinophenoxycarbonyl) phenyl) propenoyl) aminoacetate methanesulfonate; ONO 3403; ONO-3403; ONO 3403. Grades: >98%. CAS No. 181586-07-2. Molecular formula: C2H31N3O8S. Mole weight: 545.60.
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