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| Product | Description | |
|---|---|---|
| Canertinib | Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC 50 s of 7.4 and 9 nM. Canertinib is active against vaccinia virus respiratory infection in mice [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-1033; PD-183805. CAS No. 267243-28-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10367. |  |
| Canertinib | Canertinib (CI-1033;PD-183805) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC50s of 7.4 and 9 nM. Canertinib is active against vaccinia virus respiratory infection in mice. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[4-(3-Chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide. Product Category: Inhibitors. CAS No. 267243-28-7. Mole weight: 485.9. Purity: 95%+. Product ID: ACM267243287. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Canertinib | Canertinib. Group: Biochemicals. Grades: Highly Purified. CAS No. 289499-45-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C24H25CIFN5O3. US Biological Life Sciences. |  Worldwide |
| Canertinib | Canertinib is an experimental drug candidate for the treatment of cancer. It is an irreversible tyrosine-kinase inhibitor with activity against EGFR (IC50 = 0.8 nM), HER-2 (IC50 = 19 nM) and ErbB-4 (IC50 = 7 nM). Synonyms: CI-1033; PD-183805; N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide; N-[4-(3-Chloro-4-fluorophenylamino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]acrylamide; 2-propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-. Grades: >98%. CAS No. 267243-28-7. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. |  |
| Canertinib dihydrochloride | Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC 50 s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI-1033 dihydrochloride; PD-183805 dihydrochloride. CAS No. 289499-45-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10367A. | |
| Canertinib dihydrochloride | Canertinib dihydrochloride is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and radiosensitizing activities. Canertinib binds to the intracellular domains of epidermal growth factor receptor tyrosine kinases (ErbB family), irreversibly inhibiting their signal transduction functions and resulting in tumor cell apoptosis and suppression of tumor cell proliferation. This agent also acts as a radiosensitizing agent and displays synergistic activity with other chemotherapeutic agents. Uses: Antineoplastic agents. Synonyms: N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-(morpholin-4-yl)propoxy)quinazolin-6-yl)prop-2-enamide; CI1033PD183805. Grades: ≥98% (HPLC). CAS No. 289499-45-2. Molecular formula: C24H27Cl3FN5O3. Mole weight: 558.86. | |
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