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| Product | Description | |
|---|---|---|
| CC-401 | CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. The activation of JNK signaling is indentified in many immune-mediated kidney disease models. Thus, as the JNK inhibitor, CC-401 is found to be effective in these renal injury models. Synonyms: CC-401; CC 401; CC401. Grades: >98%. CAS No. 395104-30-0. Molecular formula: C22H24N6O. Mole weight: 388.47. |  |
| CC-401 dihydrochloride | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CC-401 hydrochloride | ATP-competitive, selective JNK inhibitor. Decreases c-Jun transcription activity and proliferation. Decreases cytochrome c release and caspase 3 activation. Shows anti-ischemic, anti-inflammatory and antiapoptotic effects in vivo. Synonyms: CC 401 hydrochloride; CC401 hydrochloride; CC401 HCl. Grades: >98%. CAS No. 1438391-30-0. Molecular formula: C22H25ClN6O. Mole weight: 424.93. | |
| CC-401 hydrochloride | CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CC401 HCl. CAS No. 1438391-30-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13022. |  |
| CC 401 dihydrochloride | CC 401 dihydrochloride is a potent JNK inhibitor (Ki = 25-50 nM). CC 401 competitively binds to ATP-binding site of phosphorylated JNK to inhibit JNK. Uses: Hepatoprotective. Synonyms: CC-401 dihydrochloride; CC 401 dihydrochloride; CC401 dihydrochloride; 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride. Grades: ≥98% by HPLC. CAS No. 2250025-96-6. Molecular formula: C22H24N6O.2HCl. Mole weight: 461.39. | |
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