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| Product | Description | |
|---|---|---|
| CCPA | CCPA (2-Chloro-N6-cyclopentyladenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis , etc [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 2-Chloro-N6-cyclopentyladenosine. CAS No. 37739-05-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103185. |  |
| Adenosine A1 Receptor Agonist II, CCPA ( (2R, 3R, 4S, 5R) -2- (2-chloro-6- (cyclopentylamino) -9H-purin-9-yl) -5- (hydroxymethyl) tetrahydrofuran-3, 4-diol, 2-Chloro-N6-cyclopentyladenosine) | An adenosine analog that acts as a selective, high affinity agonist for Adenosine A1 receptor (A1R) (Ki = 800 pM; 2.3uM, 18.8uM, and 42nM for human A1, A2A, A2B, A3 respectively). Shown to be centrally active following systemic administration and exhibits anti-convulsive effects. Also reported to inhibit adenylate cyclase activity in rat fat cell membrane (IC50 = 33nM). Diminishes respiratory rhythm, reduces heart rate, and enhances the activity of KATP channels. Reduces norepinephrine release by about 50% in untreated and pertussis toxin treated hearts.CAS Number:37739-05-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 37739-05-2. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?. US Biological Life Sciences. |  Worldwide |
| 2-Chloro-N6-cyclopentyladenosine | It is a selective adenosine receptor agonist and inhibits angiotensin II-induced cardiomyocyte hypertrophy through the calcineurin signaling pathway. Synonyms: CCPA; 2-Chloro-N-cyclopentyl-adenosine; (2R,3R,4S,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol; 2-chloro-N-cyclopentyl-9-pentofuranosyl-9H-purin-6-amine. Grades: ≥95% by HPLC. CAS No. 37739-05-2. Molecular formula: C15H20ClN5O4. Mole weight: 369.80. |  |
| 2-Chloro-N6-cyclopentyl Adenosine | Adenosine receptors are for treating central nervous system (CNS) disorders. Adenosine A1 receptor agonists include e.g. CCPA, 8-cyclopentyl-1,3-dipropylxanthine, R-phenylisopropyl adenosine. A2A receptor agonists include e.g. regadenoson (Lexiscan), apadenoson, binodenoson. Group: Biochemicals. Alternative Names: 2-Chloro-N-cyclopentyladenosine; CCPA. Grades: Highly Purified. CAS No. 37739-05-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Palmitoleoyl 3-carbacyclic phosphatidic acid | Palmitoleoyl 3-carbacyclic phosphatidic acid is a cyclic LPA analog containing the 16:1 fatty acid, palmitoleate, at the sn-1 position of the glycerol backbone. At 25 μM, it inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers in response to fetal bovine serum (86.9%) or LPA (99.9%) without affecting proliferation. It has been shown to inhibit autotaxin (IC50 = 620 nM). Synonyms: 3-carbacyclic PA; 3-ccPA 16:1. Grades: ≥95%. CAS No. 910228-13-6. Molecular formula: C20H37O5P. Mole weight: 388.5. | |
| Palmitoyl 3-carbacyclic phosphatidic acid | Palmitoyl 3-carbacyclic phosphatidic acid is a cyclic LPA analog containing the 16:0 fatty acid, palmitate, at the sn-1 position of the glycerol backbone. At 25 μM, it inhibits the transcellular migration of MM1 cells across mesothelial cell monolayers in response to fetal bovine serum (81.9%) or LPA (98.9%) without affecting proliferation. It has been shown to inhibit autotaxin (IC50 = 620 nM). Synonyms: 3-ccPA 16:0. Grades: ≥95%. CAS No. 476310-22-2. Molecular formula: C20H39O5P. Mole weight: 390.5. | |
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