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| Product | Description | |
|---|---|---|
| Cediranib | Cediranib (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC 50 s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD2171. CAS No. 288383-20-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10205. |  |
| Cediranib | Cediranib. Group: Biochemicals. Alternative Names: Recentin. Grades: Highly Purified. CAS No. 288383-20-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C25H27FN4O3. US Biological Life Sciences. |  Worldwide |
| Cediranib active new ester (CAEM) | Cediranib active new ester (CAEM). Uses: For analytical and research use. Group: Impurity standards. CAS No. 104797-47-9. Molecular formula: C14H10N4O3S3. Mole weight: 378.44. Catalog: APB104797479. |  |
| Cediranib dihydrochloride | Cediranib (AZD-2171; tentative trade name Recentin) is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases.The drug is being developed by AstraZeneca as a possible anti-cancer chemotherapeutic agent for oral administration. Synonyms: US brand name: Recentin. Foreign brand name: Recentin. Code name: AZD2171.AZD 2171; AZD-2171. CAS No. 288383-20-0. Molecular formula: C25H27FN4O3. Mole weight: 450.5. |  |
| Cediranib maleate | Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC 50 s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-2171 maleate. CAS No. 857036-77-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13049. | |
| Cediranib maleate | Cediranib maleate is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM. It also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM. It inhibits VEGF-stimulated proliferation with IC50 of 0.4 nM in vitro. It suppresses PDGF-AA with IC50 of 0.04 μM in MG63 cell lines. It even suppresses tubule sprouting at subnanomolar concentrations and inhibits VEGF-induced angiogenesis in vivo. It causes hypertrophy in bone growth plate and prevents luteal development in ovary. It shows broad spectrum activity in human tumor models at doses that are well tolerated. It causes regression of vascular tissues in human lung tumor xenografts. Synonyms: AZD 2171 maleate; Recentin; 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline maleate. Grades:>98%. CAS No. 857036-77-2. Molecular formula: C29H31FN4O7. Mole weight: 566.6. | |
| AZD0095 | AZD0095 is a selective and orally active MCT4 inhibitor (IC50: 1.3 nM). AZD0095 effectively inhibits the tumor growth in NCI-H358 xenograft in combination with Cediranib (HY-10205)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2750001-23-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-148517. | |
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