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| Product | Description | |
|---|---|---|
| CeMMEC1 | CeMMEC1 is an N-methylisoquinolinone derivative that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. CeMMEC1 can also inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC1; 440662-09-9; N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinoline-4-carboxamide; N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-1-oxoisoquinoline-4-carboxamide; Oprea1_520920; SCHEMBL20942542; BCP19839; EX-A1815; EiM08-22966; AKOS005754739; AC-35499; MS-25094; HY-111445; CS-0040872; Z1863671528; N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-2-METHYL-1-OXO-1,2-DIHYDRO-4-ISOQUINOLINECARBOXAMIDE. Grades: ≥98%. CAS No. 440662-09-9. Molecular formula: C19H16N2O4. Mole weight: 336.3. |  |
| CeMMEC13 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CeMMEC13 | CeMMEC13 is an isoquinolinone and a potent inhibitor of TAF1 bromodomain with IC50 of 2.1 μM. It acts on the bromodomain of TAF1 but does not bind to bromodomains of BRD4, BRD9, or CREBBP. CeMMEC13 synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC13; 1790895-25-8; 1-Methyl-2-oxo-1,2-dihydro-quinoline-4-carboxylic acid (2,3-dihydro-benzo[1,4]dioxin-6-yl)-amide; N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-methyl-2-oxo-1,2-dihydroquinoline-4-carboxamide; CHEMBL4871450; N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-2-oxoquinoline-4-carboxamide; SCHEMBL20942221; BCP25037; EX-A1816; BDBM50572136; s8329; AKOS027600530; CeMMEC13, >=98% (HPLC); CCG-267868; AC-35506; BS-15617; HY-101088; CS-0020799; C73404; A924884; Z441586532; N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-1-methyl-2-oxo-4-quinolinecarboxamide. Grades: ≥98%. CAS No. 1790895-25-8. Molecular formula: C19H16N2O4. Mole weight: 336.3. | |
| CeMMEC1 hydrochloride | CeMMEC1 is an N-methylisoquinolinone derivative that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. CeMMEC1 can also inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells. Synonyms: CeMMEC1 HCl. Grades: ≥98%. CAS No. 2095432-53-2. Molecular formula: C19H17ClN2O4. Mole weight: 372.8. | |
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