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| Product | Description | |
|---|---|---|
| Cenerimod | Cenerimod (ACT-334441) is a potent, selective and orally active S1P1 receptor modulator, with an EC 50 of 1 nM. Cenerimod shows more than 36 fold selctivity for hS1P1 over hS1P2, hS1P3, hS1P4, and hS1P5 receptor subtypes (EC 50 s=>10000, 228, 2134, and 36 nM, respectively). Cenerimod can attenuate murine experimental autoimmune encephalomyelitis (EAE) and murine sclerodermatous [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ACT-334441. CAS No. 1262414-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17606. |  |
| Cenerimod | Cenerimod is an active Lysosphingolipid receptor agonist originated by Actelion Pharmaceuticals and EC50 value is 2.7 nM. It is a S1P1/EDG1 receptor agonist and has a long-lasting immunomodulating effect through reducing the number of circulating and infiltrating T- and B-lymphocytes, without affecting their maturation, memory, or expansion. Cenerimod is in phase I/II clinical trials for the treatment of Systemic lupus erythematosus. Uses: Systemic lupus erythematosus. Synonyms: ACT-334441; ACT334441; ACT 334441; (S)-3-(4-(5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl)-2-ethyl-6-methylphenoxy)propane-1,2-diol. Grades: 98%. CAS No. 1262414-04-9. Molecular formula: C25H31N3O5. Mole weight: 453.54. |  |
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