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| Product | Description | |
|---|---|---|
| CEP-28122 | CEP-28122 is a highly potent and selective oral anaplastic lymphoma kinase inhibitor with antitumor activity in experimental human cancer models. Synonyms: CEP 28122; CEP28122; Bicyclo[2.2.1]hept-5-ene-2-carboxamide, 3-[[5-chloro-2-[[(7S)-6,7,8,9-tetrahydro-1-methoxy-7-(4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-, (1S,2S,3R,4R)-; (1S,2S,3R,4R)-3-[[5-Chloro-2-[[(7S)-6,7,8,9-tetrahydro-1-methoxy-7-(4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide. Grade: ≥95%. CAS No. 1022958-60-6. Molecular formula: C28H35ClN6O3. Mole weight: 539.07. |  |
| CEP-28122 mesylate salt | CEP-28122 mesylate salt is a highly selective orally active ALK inhibitor (IC50 = 1.9 nM). CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. Synonyms: Bicyclo[2.2.1]hept-5-ene-2-carboxamide, 3-[[5-chloro-2-[[(7S)-6,7,8,9-tetrahydro-1-methoxy-7-(4-morpholinyl)-5H-benzocyclohepten-2-yl]amino]-4-pyrimidinyl]amino]-, (1S,2S,3R,4R)-, methanesulfonate (1:1); CEP-28122 methanesulfonic acid; (1S,2S,3R,4R)-3-((5-chloro-2-(((S)-1-methoxy-7-morpholino-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl)amino)pyrimidin-4-yl)amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide methanesulfonic acid; CEP28122 mesylate salt; CEP 28122 mesylate salt. Grade: 99%. CAS No. 2070009-30-0. Molecular formula: C29H39ClN6O6S. Mole weight: 635.17. | |
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