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Ceramide 1-phosphate is a bioactive lipid and one of the key components of sphingolipids. Ceramide 1-phosphate playing diverse roles in cellular behaviors such as cell differentiation, migration, proliferation and death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 128543-23-7. Pack Sizes: 1 mg. Product ID: HY-P2982.
C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid found in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. Cer(t18:0/18:0) consists of a phytosphingosine backbone amine linked to a C18 fatty acid chain. Cer(t18:0/18:0) has the function of regulating apoptosis, cell differentiation, proliferation of smooth muscle cells and inhibition of mitochondrial respiratory chain. It also suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue. Formulations containing cer(t18:0/18:0) have been used as skin protectants in cosmetics as they reduce water loss and prevent epidermal dehydration and irritation. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: N-Stearoyl phytosphingosine. CAS No. 34354-88-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141582.
ceramide cholinephosphotransferase
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. The systematic name of this enzyme class is CDP-choline:N-acylsphingosine cholinephosphotransferase. This enzyme is also called phosphorylcholine-ceramide transferase. This enzyme participates in sphingolipid metabolism. Group: Enzymes. Synonyms: phosphorylcholine-ceramide transferase. Enzyme Commission Number: EC 2.7.8.3. CAS No. 9026-14-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3329; ceramide cholinephosphotransferase; EC 2.7.8.3; 9026-14-6; phosphorylcholine-ceramide transferase. Cat No: EXWM-3329.
ceramide glucosyltransferase
Sphingosine and dihydrosphingosine can also act as acceptors; CDP-glucose can act as donor. Group: Enzymes. Synonyms: UDP-glucose:ceramide glucosyltransferase; ceramide:UDP-Glc glucosyltransferase; uridine diphosphoglucose-ceramide glucosyltransferase; ceramide:UDP-glucose glucosyltransferase; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.80. CAS No. 37237-44-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2621; ceramide glucosyltransferase; EC 2.4.1.80; 37237-44-8; UDP-glucose:ceramide glucosyltransferase; ceramide:UDP-Glc glucosyltransferase; uridine diphosphoglucose-ceramide glucosyltransferase; ceramide:UDP-glucose glucosyltransferase; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase. Cat No: EXWM-2621.
ceramide kinase
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:ceramide 1-phosphotransferase. This enzyme is also called acylsphingosine kinase. This enzyme participates in sphingolipid metabolism. Group: Enzymes. Synonyms: acylsphingosine kinase. Enzyme Commission Number: EC 2.7.1.138. CAS No. 123175-68-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2969; ceramide kinase; EC 2.7.1.138; 123175-68-8; acylsphingosine kinase. Cat No: EXWM-2969.
Ceramide kinase inhibitor,k1
Heterocyclic Organic Compound. CAS No. 1258005-85-4. Molecular formula: C21H28O4. Mole weight: 344.4. Appearance: White solid. Purity: 0.96. Catalog: ACM1258005854.
Ceramides
Ceramide Powder is the latest moisturizer developed recently. It is a type of phospholipid with ceramide as a skeleton. Ceramide phosphocholine and ceramide phosphoethanolamine are the main components. Phospholipid is the main component of the cell membrane, and the stratum corneum 40%~50% sebum is composed of Ceramide Powder. Alternative Names: (Z)-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadec-9-enamide. CAS No. 100403-19-8. Molecular formula: C24H47NO3. Mole weight: 397.63. Appearance: Crystalline solid. Purity: 0.98. Density: 0.928 g/cm³. ECNumber: 309-560-3. Catalog: ACM100403198.
1-O-Acyl-ceramide
1-O-Acyl-ceramide. Group: Biochemicals. Alternative Names: 1-oleoyl-N-Heptadecanoyl-D-erythro-sphingosine; C17:0, d18:1 ceramide-1-O-18:1. Grades: Highly Purified. CAS No. 1246303-19-4. Pack Sizes: 5mg. Molecular Formula: C53H101NO4, Molecular Weight: 816.37. US Biological Life Sciences.
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1-O-Benzoyl C2 Ceramide
C2 Ceramide derivative. Group: Biochemicals. Alternative Names: 1-O-benzoyl-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamide; 1-O-benzoyl-N-acetyl-D-sphingosine; 1-O-benzoyl Acetyl Ceramide; 1-O-benzoyl N-Acetylsphingosine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
The enzyme, characterized from yeast and mammals, catalyses the hydroxylation of carbon 2 of long- or very-long-chain fatty acids attached to (4R)-4-hydroxysphinganine during de novo ceramide synthesis. The enzymes from yeast and from mammals contain an N-terminal cytochrome b5 domain that acts as the direct electron donor to the desaturase active site. The newly introduced 2-hydroxyl group has R-configuration. cf. EC 1.14.18.7, dihydroceramide fatty acyl 2-hydroxylase. Group: Enzymes. Synonyms: FA2H (gene name); SCS7 (gene name). Enzyme Commission Number: EC 1.14.18.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0968; 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase; EC 1.14.18.6; FA2H (gene name); SCS7 (gene name). Cat No: EXWM-0968.
6-Amino-6-deoxy α-Galactosyl-C18-ceramide
α-Galactosyl-C18-ceramide derivative. A potent stimulator of human T cells. Molecular formula: C42H82N2O7. Mole weight: 727.11.
Galactosylceramides play an important roles in promoting th. Group: Biochemicals. Alternative Names: GalCer. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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a-Galactosyl-C18-ceramide
Galactosylceramides play an important roles in promoting th. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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α-Galactosyl-C18-ceramide
Galactosylceramides play a significant role in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have critical immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: N-[(1S,2R,3E)-1-[(α-D-Galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]octadecanamide. Grades: 97%. CAS No. 148347-40-4. Molecular formula: C42H81NO8. Mole weight: 728.09.
b-D-Glucosyl C4-ceramide
b-D-Glucosyl C4-ceramide, a pivotal element extensively employed in the biomedical sector owing to its commendable therapeutic capacities, exhibits an imperative presence in combating numerous ailments, such as cancer and neurodegenerative disorders. Primarily acting as a regulator within cellular signaling cascades, it concomitantly stimulates cellular proliferation and differentiation whilst impeding aberrant processes. Synonyms: [R-[R*,S*-(E)]]-N-[1-[(b-D-Glucopyranosyloxy)methyl]-2-hydroxy-3-heptadecenyl]butanamide. CAS No. 111956-45-7. Molecular formula: C28H53NO8. Mole weight: 531.72.
Galactosylceramides play a significant role in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have critical immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: C18-Cerebroside; D-galactosyl-β-1,1'-N-stearoyl-D-erythro-sphingosine. Grades: >99%. CAS No. 36271-49-5. Molecular formula: C42H81NO8. Mole weight: 728.09.
β-Galactosyl-C18-ceramide Tetraacetate
β-Galactosyl-C18-ceramide Tetraacetate is an intermediate formed in the β-Galactosyl-C18-ceramide synthesis, which is a galactosylceramides involved in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. They have shown to have important immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma. Synonyms: (2R,3S,4S,5R,6R)-2-(Acetoxymethyl)-6-(((2S,3R,E)-3-hydroxy-2-stearamidooctadec-4-en-1-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C50H89NO12. Mole weight: 896.24.
Requires Mn2+. Group: Enzymes. Synonyms: uridine diphosphoacetylglucosamine-acetyllactosaminide β1?3-acetylglucosaminyltransferase; poly-N-acetyllactosamine extension enzyme; UDP-N-acetyl-D-glucosamine:β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide β-1,3-acetylglucosaminyltransferase. Enzyme Commission Number: EC 2.4.1.163. CAS No. 85638-39-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2388; β-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide β-1,3-acetylglucosaminyltransferase; EC 2.4.1.163; 85638-39-7; uridine diphosphoacetylglucosamine-acetyllactosaminide β1?3-acetylglucosaminyltransferase; poly-N-acetyllactosamine extension enzyme; UDP-N-acetyl-D-glucosamine:β-D-galactosyl-1,4-N-acetyl-β-D-glucosaminyl-1,3-β-D-galactosyl-1,4-β-D-glucosylceramide β-1,3-acetylglucosaminyltransferase. Cat No: EXWM-2388.
Ceramide is one of the simplest sphingolipids, consisting of a sphingosine base N-linked to a fatty acid, and is a membrane mediator for cell-signaling events. N-Acyl chain length of membrane ceramides can influence bidimensional transitions, condensed domain morphology, and interfacial thickness. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]dodecanamide; N- [ (1S, 2R, 3E) -2-Hydroxy-1- (hydroxymethyl) -3-heptadecenyl] dodecanamide; [R- [R*, S*- (E) ] ] -N- [2-Hydroxy-1- (hydroxymethyl) -3-heptadecenyl] dodecanamide; N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine. Grades: Highly Purified. CAS No. 74713-60-3. Pack Sizes: 5mg. US Biological Life Sciences.
C12-Ceramide (N-Lauroyl-D-erythro-sphingosine), a naturally occurring ceramide, is formed by hydrolysis of C12 sphingomyelin. C12-Ceramide can enhance the Doxorubicin toxicity in MDA-MB-231 cells. C12-Ceramide also can be used to diagnose types A and B Niemann-Pick disease [1] [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine. CAS No. 74713-60-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100353.
C14-Ceramide
C14-Ceramide. Group: Biochemicals. Alternative Names: N-Myristoyl-D-sphingosine; N- [ (1S, 2R, 3E) -2-hydroxy-1- (hydroxymethyl) -3-heptadecenyl] tetradecanamide; N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, [R-[R*,S*-(E)]]tetradecanamide. Grades: Highly Purified. CAS No. 34227-72-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C32H63NO3. US Biological Life Sciences.
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C14 Ceramide (d18:1/14:0)
C14 Ceramide (d18:1/14:0) is an endogenous ceramide produced by ceramide synthetase 6, which can be used for Parkinson's and diabetes research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 123408-74-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-124177A.
C14 Ceramide (N-Myristoyl-D-sphingosine)
C14 Ceramide (N-Myristoyl-D-sphingosine). Group: Biochemicals. Alternative Names: N-Myristoyl-D-sphingosine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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C16-Ceramide
C16-Ceramide. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-hexadecanamide; (2S, 3R, 4E) -2-N-Palmitoyl octadecasphinga-4-ene . Grades: Highly Purified. CAS No. 24696-26-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C34H67NO3. US Biological Life Sciences.
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C16-Ceramide
C16-Ceramide is a natural small molecule activating p53 through the direct and selective binding [1]. Uses: Scientific research. Group: Natural products. CAS No. 24696-26-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100354.
C16 Ceramide-1-phosphate (d18:1/16:0) ammonium
C16 Ceramide-1-phosphate (d18:1/16:0) (ammonium) (C16 Ceramide-1-phosphate (ammonium); Ceramide-1-phosphate (d18:1/16:0) (ammonium)) is an ester product. Uses: Scientific research. Group: Signaling pathways. Alternative Names: C16 Ceramide-1-phosphate ammonium; Ceramide-1-phosphate (d18:1/16:0) ammonium; CerP(d18:1/16:0) ammonium. CAS No. 1246303-22-9. Pack Sizes: 5 mg. Product ID: HY-145467.
C16 Ceramide-1-phosphate (d18:1/16:0) ammonium salt
C16 Ceramide-1-phosphate (C16 C1P) is one of the main forms of C1P found in cells. It is created by phosphorylation of by ceramide kinase. It activates cytosolic phospholipase A2α (PLA2α) and stimulates the release of arachidonic acid in A549 cells. Synonyms: C16 C1P; C16 Ceramide-1-phosphate; N-(hexadecanoyl)-sphing-4-enine-1-phosphate; CerP(d18:1/16:0). Grades: ≥98%. CAS No. 1246303-22-9. Molecular formula: C34H71N2O6P. Mole weight: 634.91.
A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphatase in T9 cells; induces EGF receptor phosphorylation in A-431 cells; stimulates ceramide-activated protein kinase. Group: Biochemicals. Alternative Names: N-Palmitoyl-D-Sphingosine; N-Hexadecanoyl-D-sphingosine; Palmitoyl Ceramide. Grades: Highly Purified. CAS No. 24696-26-2. Pack Sizes: 5mg. US Biological Life Sciences.
It is a glycosphingolipid that contains a galactose moiety attached to a ceramide acylated with palmitic acid. Synonyms: D-galactosyl-α-1,1'-N-palmitoyl-D-erythro-sphingosine; Hexadecanamide, N-[(1S,2R,3E)-1-[(α-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-; α C16 Galactosylceramide (d18:1/16:0); C16 α-D-galactosyl ceramide; N-(hexadecanoyl)-1-α-galactosyl-sphing-4-enine; N-((2S,3R,E)-3-hydroxy-1-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)octadec-4-en-2-yl)palmitamide; N-[(2S,3R,4E)-1-(α-D-Galactopyranosyloxy)-3-hydroxy-4-octadecen-2-yl]hexadecanamide; α-GalCer(d18:1/16:0). Grades: >99%. CAS No. 2260795-77-3. Molecular formula: C40H77NO8. Mole weight: 700.04.
C16 PEG2000 Ceramide
C16 PEG2000 Ceramide is a polyethylene glycolylated ceramide. C16 PEG2000 Ceramide can be used for lipid carrier to delivery. C16 PEG2000 Ceramide induces autophagy. C16 PEG2000 Ceramide can be used for cancer research [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: C16 PEG Ceramide (MW 2000). CAS No. 212116-78-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-144005.
C18:1-Ceramide
C18:1-Ceramide is a ceramide subspecies. C18:1-Ceramide can be used in the study of type 2 diabetes [1]. Uses: Scientific research. Group: Natural products. CAS No. 5966-28-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141578.
C18-Ceramide is a bioactive molecule with multiple functions in cells, can cross the blood-brain barrier, not a traditional agonist or inhibitor targeting a single site. It can act on multiple cellular targets, such as proteins related to endoplasmic reticulum stress (e.g., ATF-4, XBP-1, CHOP), proteins in the PI3K/AKT signaling pathway, and SNARE complex proteins. It exerts activities like inducing cell death, promoting autophagy, and regulating exocytosis through mechanisms such as activating endoplasmic reticulum stress, inhibiting the PI3K/AKT signaling pathway, and affecting lipid raft - related functions. It can be used in research on the mechanism of neuronal injury in the field of neuroscience and in the treatment research of cancers such as glioma in the field of oncology [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 2304-81-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100355.
C18 Ceramide-13C2,D2
The sphingolipid ceramide. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]octadecanamide-13C2,D2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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C18-Ceramide-d7
C18-Ceramide-d 7 is deuterium labeled C18-Ceramide. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1840942-14-4. Pack Sizes: 500 μg (1.75 mM * 500 μL in Methanol:Chloroform (10:90)); 1 mg; 5 mg. Product ID: HY-100355S1.
The sphingolipid ceramide is a potent inhibitor of the mitochondrial permeability transition pore. Group: Biochemicals. Alternative Names: N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]octadecanamide; D-erythro-1,3-Dihydroxy-2-octadecanoylamido-trans-4-octadecene; N-Stearoyl-C18-sphingosine; N-Stearoyl-D-erythro-sphingosine; N-Stearoyl-D-sphingosine; N-Stearoylsphingenine; N-Stearoylsphingosine. Grades: Highly Purified. CAS No. 2304-81-6. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C36H71NO3, Molecular Weight: 565.95. US Biological Life Sciences.
C18 L-erythro Ceramide is a naturally occurring ceramide and stereoisomer of C18 ceramide. It can inhibit rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 8.8 μM. Synonyms: L-erythro Cer(d18:1/18:0); L-erythro Ceramide (d18:1/18:0); N-octadecanoyl-L-erythro-sphingosine. Grades: ≥98%. CAS No. 252039-52-4. Molecular formula: C36H71NO3. Mole weight: 565.95.
C18 L-threo Ceramide (d18:1/18:0)
C18 L-threo Ceramide is a synthetic ceramide and stereoisomer of C18 ceramide that has been used for structural characterization of natural sphingolipids. It inhibits rat brain mitochondrial ceramidase (mt-CDase) with an IC50 value of 16.8 μM. Synonyms: N-octadecanoyl-L-threo-sphingosine; L-threo Cer(d18:1/18:0); L-threo Ceramide (d18:1/18:0). Grades: ≥98%. CAS No. 95037-06-2. Molecular formula: C36H71NO3. Mole weight: 565.95.
C20 Ceramide
C20 Ceramide is a natural 20:0 ceramide that is abundant in the brain [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: N-Arachidoyl-D-sphingosine. CAS No. 7344-2-7. Pack Sizes: 1 mg. Product ID: HY-112016.
C22 Ceramide (N-[(3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-docosanamide). Group: Biochemicals. Alternative Names: N-[(3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-docosanamide. Grades: Highly Purified. CAS No. 869501-30-4. Pack Sizes: 2mg. US Biological Life Sciences.
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C24:1 b-D-Galactosyl ceramide
C24:1 b-D-Galactosyl ceramide is a renowned compound prevalent in the ever-evolving biomedical realm, specifically tailored for the research of diverse afflictions, including Gaucher disease and Fabry disease. Synonyms: Galactosyl-b-1,1 N-nervonoyl-D-erythro-sphingosine. Grades: >99%. CAS No. 17283-91-9. Molecular formula: C48H91NO8. Mole weight: 810.24.
C24:1Ceramide
C24:1Ceramide. Group: Biochemicals. Alternative Names: Nervonic ceramide. Grades: Highly Purified. CAS No. 54165-50-0. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C42H81NO3. US Biological Life Sciences.
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