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cGMP, a cyclic guanosine monophosphate, possesses an essential role in governing numerous physiological processes. Significantly employed as a pharmacological focal point in the biomedical realm to combat the likes of hypertension and pulmonary arterial hypertension, its potency is immense. Furthermore, it is intricately involved in the signal transduction pathways of selected neurotransmitters and hormones. Synonyms: Guanosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C10H12N5O7P (free acid). Mole weight: 345.20 (free acid).
cGMP-AM
cGMP-AM is a precursor of cGMP, the second messenger. The polar active analogue is released after the metabolism of cGMP-AM by esterases. Synonyms: Guanosine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 95% by HPLC for mixture of isomers. CAS No. 164007-71-0. Molecular formula: C13H16N5O9P. Mole weight: 417.3.
cGMP Dependent Kinase Inhibitor Peptide
cGMP Dependent Kinase Inhibitor Peptide. Group: Biochemicals. Grades: Purified. CAS No. 82801-73-8. Pack Sizes: 1mg. US Biological Life Sciences.
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cGMP Dependent Kinase Inhibitor Peptide
PKG Inhibitor is a competitive inhibitor of cGMP-dependent protein kinase (PKG). It is an analog of a substrate peptide corresponding to a phosphorylation site of histone H2B, and inhibits phosphorylation of intact histones by PKA. Synonyms: cGMP Dependent Kinase Inhibitor Peptide. Grades: >98%. CAS No. 82801-73-8. Molecular formula: C38H74N18O10. Mole weight: 943.12.
cGMP-dependent protein kinase
CGMP is required to activate this enzyme. The enzyme occurs as a dimer in higher eukaryotes. The C-terminal region of each polypeptide chain contains the catalytic domain that includes the ATP and protein substrate binding sites. This domain catalyses the phosphorylation by ATP to specific serine or threonine residues in protein substrates. The enzyme also has two allosteric cGMP-binding sites (sites A and B). Binding of cGMP causes a conformational change that is associated with activation of the kinase. Group: Enzymes. Synonyms: 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Enzyme Commission Number: EC 2.7.11.12. CAS No. 141588-27-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3131; cGMP-dependent protein kinase; EC 2.7.11.12; 141588-27-4; 3':5'-cyclic GMP-dependent protein kinase; cGMP-dependent protein kinase Iβ; guanosine 3':5'-cyclic monophosphate-dependent protein kinase; PKG; PKG 1α; PKG 1β; PKG II; STK23. Cat No: EXWM-3131.
1-NH2-cGMP
1-NH2-cGMP is a selective cGMP analogue that has a higher affinity of site A in cGK, and it is commonly used for synergism studies. Synonyms: 1- Aminoguanosine- 3', 5'- monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 78033-42-8. Molecular formula: C10H12N6O7P · Na. Mole weight: 382.2.
2',3'-cGMP
2',3'-cGMP, a cyclic nucleotide with profound significance in the biomedical sector, takes center stage within this product description. Employed primarily as a research instrument, it facilitates an in-depth exploration of intracellular signaling cascades across diverse biological spectrums. Furthermore, 2',3'-cGMP assumes an indispensable role in overseeing cellular proliferation and differentiation. This versatile product harbors immense potential, warranting its employment in the realm of drug discovery. Synonyms: Guanosine- 2', 3'- cyclic monophosphate, sodium salt. Grades: ≥ 97 % by HPLC. CAS No. 15718-49-7. Molecular formula: C10H11N5O7P · Na. Mole weight: 367.2.
2',3'-cGMP sodium
2',3'-cGMP sodium, a cGMP analogue, is an intermediate of RNA catalytic cleavage by binase [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Guanosine 2',3'-cyclic monophosphate sodium salt. CAS No. 15718-49-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N8245.
2'-AEC-cGMP-Agarose
2'-AEC-cGMP-Agarose is the protein kinase G activator cGMP immobilized on agarose by an aminoethylcarbamoyl spacer, which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (2- Aminoethylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel.
2'-AEC-cGMP / EDA-cGMP
2'-AEC-cGMP is a cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 2'- O- (2- Aminoethylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. Molecular formula: C13H18N7O8P. Mole weight: 431.3.
2'-AHC-cGMP
2'-AHC-cGMP is a cGMP analogue used for immobilization as an affinity ligand or for coupling of labelling structures such as fluorophores. Synonyms: 2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 1262749-60-9. Molecular formula: C17H26N7O8P. Mole weight: 487.4.
2'-AHC-cGMP-Agarose
2'-AHC-cGMP-Agarose is the protein kinase G activator cGMP immobilized on agarose by an aminohexylcarbamoyl spacer which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as some phosphodiesterases. Synonyms: 2'- O- (6- Aminohexylcarbamoyl)guanosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel.
2-AH-cGMP
2-AH-cGMP is a ligand in affinity chromatography of cGMP binding proteins and can be modified with fluorophores. Synonyms: 2-AH-CGMP SODIUM SALT; 205368-58-7. Grades: ≥ 98% by HPLC. CAS No. 205368-58-7. Molecular formula: C16H25N6O7P. Mole weight: 444.4.
2-AH-cGMP-Agarose
2-AH-cGMP-Agarose is the second messenger cGMP immobilized on agarose by an aminohexyl spacer which can be used in affinity chromatography of cyclic nucleotide-responsive proteins such as protein kinases, phosphodiesterases and others. Synonyms: N2- (6- Aminohexyl)guanosine- 3', 5'- cyclic monophosphate; immobilized on agarose gel.
2-Biotin-14-cGMP
2-Biotin-14-cGMP, a potent cyclic nucleotide derivative, serves as an exemplary research tool for comprehensively investigating a vast array of signaling pathways intricately interlaced with cGMP. Furthermore, the use of this compound serves as a noteworthy means for evaluating the cGMP-dependent protein kinase (PKG) activity pertaining to an extensive spectrum of diseases. Grades: ≥ 98% by HPLC. Molecular formula: C32H49N9O10PS · Na. Mole weight: 805.8.
2'-dcGMP
2'-dcGMP is an analogue of cGMP, which is a protein kinase G inactive agent. Synonyms: 2'- Deoxyguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 93919-42-7. Molecular formula: C10H11N5O6P · Na. Mole weight: 351.2.
2'-[DY505-05]-AHC-cGMP
2'-[DY505-05]-AHC-cGMP is a fluorescent cGMP analogue (λexc505 nm, λem530 nm) that can be used for phosphodiesterase studies. Synonyms: 2'- O- (6- [DY-505-05]- aminohexylcarbamoyl))guanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H37N9O12P · Na. Mole weight: 865.7.
2'-Fluo-AHC-cGMP
2'-Fluo-AHC-cGMP is a fluorescent cGMP analogue that can be used for phosphodiesterase studies. Synonyms: 2'- (6-[Fluoresceinyl]aminohexylcarbamoyl) guanosine-3', 5'-cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H35NNa7O14P. Mole weight: 867.7.
2-Me-cGMP
2-Me-cGMP is an analogue of cGMP used for cGMP receptor mapping studies. Grades: ≥ 99% by HPLC. CAS No. 205368-54-3. Molecular formula: C11H13N5O7P · Na. Mole weight: 381.2.
2'- (N-Methylanthraniloyl) guanosine 3',5'-Cyclicmonophosphate, Sodium Salt (MANT-cGMP)
A blue fluorescent derivative of cGMP is a useful substrate the assay of cyclic nucleotide phosphdiesterase. Also inhibits calmodulin-dependent activation of cyclic nucleotide phosphodiesterase by peptide segments of HIV envelope glycoproteins has been monitored using MANT-cGMP.Fluorescence: max. Abs. 359nm; max. Em. 448nm; e x 10-3: 5.2. Group: Biochemicals. Alternative Names: Cyclic 3,5-(hydrogen phosphate) 2-[2-(methylamino)benzoate] Guanosine Monosodium Salt; MANT-cGMP. Grades: Highly Purified. CAS No. 221905-46-0. Pack Sizes: 5mg. US Biological Life Sciences.
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2'-O-MB-cGMP
2'-O-MB-cGMP is a precursor of cGMP. cGMP is released after the metabolism of 2'-O-MB-cGMP by esterases. Compared to cGMP, it has more lipophilic and membrane-permeant properties. Synonyms: 2'- O- Monobutyrylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 58329-72-9. Molecular formula: C14H17N5O8P · Na. Mole weight: 437.3.
2'-O-Me-cGMP
2'-O-Me-cGMP is a polar analogue of cGMP that activate neither protein kinase G nor Epac. It exhibits an inactive effect in patch clamp applications and can be used for receptor mapping studies. Synonyms: 2'- O- Methylguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 949909-73-3. Molecular formula: C11H13N5O7P · Na. Mole weight: 381.2.
2'-O-MS-cGMP
2'-O-MS-cGMP is a cGMP analogue, which is used for coupling of ligands including proteins for ELISA. Synonyms: 2'- O- Monosuccinylguanosine- 3', 5'- cyclic monophosphate, free acid. Grades: ≥ 98% by HPLC. CAS No. 39118-26-8. Molecular formula: C14H16N5O10P. Mole weight: 445.3.
2'-O-MS-TME-cGMP
2'-O-MS-TME-cGMP is an analogue of cGMP, which is used for radio-iodination in cGMP immunoassays. Synonyms: 2'- O- Monosuccinylguanosine- 3', 5'- cyclic monophosphate, tyrosylmethyl ester, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 104872-93-7. Molecular formula: C24H26N6O12P · Na. Mole weight: 644.5.
2'-TAMRA-AEC-cGMP
2'-TAMRA-AEC-cGMP is a fluorescent cGMP analogue (λexc555 nm, λem580 nm) that can be used for phosphodiesterase studies. Synonyms: 2'- O- (2- [Tetramethylrhodaminyl] aminoethylcarbamoyl) guanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H37N9O12P · Na. Mole weight: 865.7.
2'-TAMRA-AHC-cGMP
2'-TAMRA-AHC-cGMP is a fluorescent cGMP analogue (λexc555 nm, λem580 nm) that can be used for phosphodiesterase studies. Synonyms: 2'- O- (6- [Tetramethylrhodaminyl] aminohexylcarbamoyl) guanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C42H45N9O12P · Na. Mole weight: 921.8.
4-N3-PET-8-Biotin-11-cGMP
4-N3-PET-8-Biotin-11-cGMP is a cGMP analogue used for photoaffinity labelling of cGMP-responsive receptors. Grades: ≥ 95% by HPLC. Molecular formula: C36H44N12O10PS2 · Na. Mole weight: 922.9.
4-N3-PET-8-Br-cGMP
4-N3-PET-8-Br-cGMP is an analogue used for photoaffinity labelling of cGMP-responsive receptors, and an isozyme-selective activator of cGMP-dependent protein kinase I α and &beta. Synonyms: β- (4- Azidophenyl)- 1, N2- etheno- 8- bromoguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 97% by HPLC. Molecular formula: C18H13BrN8O7P · Na. Mole weight: 587.2.
6-Bn-cGMP
6-Bn-cGMP, a cyclic nucleotide derivative, possesses a remarkable significance as a research tool in the field of cell and tissue study, especially concerning the impacts of cGMP signaling pathways. With its role in regulating smooth muscle contraction and platelet function, it has potential in being a cGMP agonist for cardiovascular, neurological, and urological studies. This product serves as a promising chemical for research investigation on various disorders, aiming for substantial therapeutic advancements. Molecular formula: C17H17N5O7P · Na. Mole weight: 457.3.
6-BT-cGMP
6-BT-cGMP is a cyclic guanosine monophosphate (cGMP) analogue, unraveling the enigmatic signaling pathways and biological ramifications of cGMP across diverse cellular manifestations. Furthermore, its resourcefulness extends to the exploration of therapeutics modulating maladies associated with disrupted cGMP signaling, encompassing cardiovascular maladies and select forms of malignancy alike. Synonyms: 6- Benzylthioguanosine- 3', 5'- cyclic monophosphate. Molecular formula: C17H17N5O6PS · Na. Mole weight: 473.4.
6-HT-cGMP
6-HT-cGMP, a cyclic guanosine monophosphate (cGMP) analog, has been subject to extensive research as a prospective therapy for cardiovascular ailments. With vasoconstriction being a leading cause of such diseases, extensive studies have shown that 6-HT-cGMP act as a vasodilator. Animal models have indicated that it can increase coronary blood flow, giving it potential clinical implications. Furthermore, 6-HT-cGMP is promising in the treatment of erectile dysfunction. A comprehensive understanding of its properties and mechanisms is imperative as it shows great potential in treating these prevalent conditions. Synonyms: 6- Hexylthioguanosine- 3', 5'- cyclic monophosphate. Molecular formula: C16H23N5O6PS · Na. Mole weight: 467.4.
7-CH-cGMP
7-CH-cGMP, a remarkable biomedicine product, marvellously assists in the treatment of Parkinson's disease as well as select cancer types. This extraordinary compound operates as a stimulant for cyclic nucleotide-dependent protein kinase G (PKG), effectively governing pivotal cellular phenomena such as cell proliferation, apoptosis, and neurotransmission. The intricate mechanisms through which 7-CH-cGMP exerts its therapeutic effects continue to captivate the minds of researchers in the ever-evolving realm of biomedicine. Synonyms: 7- Deazaguanosine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 81611-03-2. Molecular formula: C11H12N4O7P · Na. Mole weight: 366.2.
8-[(6-Amino)hexyl]-amino-cGMP
8-[(6-Amino)hexyl]-amino-cGMP, a derivative of cyclic guanosine monophosphate (cGMP), displays potential for therapeutic use in diseases like hypertension and erectile dysfunction. This analogue's efficacy lies within its ability to enhance smooth muscle relaxation and trigger vasodilation. With the potential to alleviate the symptoms of these ailments, 8-[(6-Amino)hexyl]-amino-cGMP offers a promising avenue for further study and development. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P (free acid). Mole weight: 459.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - 5/6-TAMRA
8-[(6-Amino)hexyl]-amino-cGMP - 5/6-TAMRA is a remarkable compound, unveiling intricate prospects for the research of multifarious ailments. With its fluorescence probing attributes, it astutely unravels the enigmatic intricacies of cyclic guanosine monophosphate (cGMP)-dependent cellular processes. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with 5/6-TAMRA. Grades: ≥ 95% by HPLC. Molecular formula: C41H46N9O11P (free acid). Mole weight: 871.84 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - 5-FAM
8-[(6-Amino)hexyl]-amino-cGMP - 5-FAM, a fluorescent probe, is widely used in investigating the intricate cyclic guanosine monophosphate (cGMP) in biological systems. It's highly proficient in recognizing shifts in cGMP levels, a crucial factor in hypertension, heart failure, and erectile dysfunction. This powerful probe acts as a pivotal tool in drug discovery targeted towards cGMP signaling pathways; thus, offering numerous possibilities to advance drug development. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with 5 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H36N7O13P (free acid). Mole weight: 817.70 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - 6-FAM
8-[(6-Amino)hexyl]-amino-cGMP - 6-FAM is a fluorescent cGMP analogue commonly used in the study of cGMP signaling pathways. It is also utilized in diagnostics and drug research for diseases such as cardiovascular disease and erectile dysfunction. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with 6 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H36N7O13P (free acid). Mole weight: 817.70 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - 6-JOE
8-[(6-Amino)hexyl]-amino-cGMP - 6-JOE is a compound ingeniously devised to regulate the multifarious signaling pathways orchestrating cellular multiplication and programmed cell death. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with 6-JOE, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C39H37Cl2N6O16P (free acid). Mole weight: 946.14 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - 6-ROX
8-[(6-Amino)hexyl]-amino-cGMP - 6-ROX is the perfect solution for scientists who seek to study the intricate mechanisms behind cyclic nucleotide metabolism in cells. With its fluorescent characteristics, monitoring cGMP synthesis and degradation is made simpler than ever before. Moreover, by utilizing this product, researchers are able to delve deeper into the root causes of diseases that are associated with impaired cGMP signaling, including hypertension and heart failure. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with 6-ROX. Grades: ≥ 95% by HPLC. Molecular formula: C49H54N9O11P (free acid). Mole weight: 975.99 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-390
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-390, a luminescent marker, offers researchers a viable tool to evaluate cyclic nucleotide signaling pathways. It furnishes a mechanism to assay guanylyl cyclase action, as well as drug responsiveness. Moreover, its application has the potential for wider clinical utilization including drug delivery and cancer diagnosis. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 390, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C36H49N8O10P (free acid). Mole weight: 784.80 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-425
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-425 is a fluorescent probe used to measure cyclic guanosine monophosphate (cGMP) levels in biological systems. It is a valuable tool in studying diseases such as pulmonary hypertension and erectile dysfunction where cGMP regulation is disrupted. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 425, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C38H51N8O12P (free acid). Mole weight: 842.84 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-465
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-465 is a fluorescent dye widely employed in diverse biomedical applications, showcasing immense potential in drug discovery, molecular imaging and cellular studies. It serves the pivotal purpose of labeling proteins, nucleic acids and biomolecules to facilitate precise tracking and visualization. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 465. Grades: ≥ 95% by HPLC. Molecular formula: C33H41N10O8P (free acid). Mole weight: 736.71 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-488
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-488, a fluorescent probe, has multifaceted applications in biomedicine research. One of its primary functions is monitoring cyclic guanosine monophosphate (cGMP) levels, which helps in understanding the signals that govern critical cellular activities. In addition, researchers use it to explore cell signaling mechanisms in the context of various diseases such as hypertension, cardiovascular diseases, and related disorders. All in all, this innovative probe represents the vanguard of medical research looking to investigate complex biological systems. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 488, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C41H47N10O16PS2 (free acid). Mole weight: 1030.24 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-495
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-495, a biochemical tool renowned for its high potency, has been prudently curated for biomedical research. This efficacious molecule is often employed to investigate the impacts of intracellular cyclic nucleotide signaling pathways, with its remarkably sensitive fluorophore, ATTO-495, facilitating the detection and visualization of the molecule in cellular environments. The versatility of the product sees its usability extend to numerous studies relating to complex medical conditions such as hypertension, cardiovascular disorders, and devastating cancer, among others. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 495. Grades: ≥ 95% by HPLC. Molecular formula: C37H49N10O8P (free acid). Mole weight: 792.82 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-532
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-532 is a fluorescent dye with excitation/emission at 532/555 nm. It can be employed as a labeling agent for real-time imaging of cGMP signaling pathways and visualization of specific drug targets in various in vitro and in vivo biomedical studies. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 532, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C45H55N10O16PS2 (free acid). Mole weight: 1086.30 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-540Q
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-540Q is a fluorescently labeled cyclic guanosine monophosphate (cGMP) derivative, utilized in compound for visualization and detection of cGMP signaling pathways. This compound aids in studying cardiovascular diseases, such as hypertension and heart failure, where cGMP dysregulation is implicated. It enables precise monitoring and quantification of cGMP levels, facilitating comprehensive understanding of its role in disease progression and drug design. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 540Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 540Q (free acid). Mole weight: 999.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-550
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-550 is a fluorescent probe whose purpose is monitoring of intracellular cGMP levels in living cells. This product is employed in studies connected to the cGMP signaling pathway and finding treatments of cardiovascular and metabolic ailments. The said properties of this fluorescent probe make it a crucial tool in biomedical research and scientific studies investigating intracellular processes in living systems, proving its worth in observing and studying cellular functions in utmost detail. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 550, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 550 (free acid). Mole weight: 1034.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-565
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-565, an illuminating dye utilized extensively in biomedical research, binds to cGMP, a vital molecule that regulates different physiological processes like platelet aggregation, blood pressure regulation, and smooth muscle relaxation. Visualizing and scrutinizing the cGMP signaling in cells and tissues, measuring the activity of enzymes responsible for synthesizing or hydrolyzing cGMP, ATTO-565 caters to all of your specific experimental demands and unravels the answers locked deep within the biochemistry of the cell. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 565. Grades: ≥ 95% by HPLC. Molecular formula: C47H54N9O11P (free acid). Mole weight: 951.97 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-580Q
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-580Q, a fluorescent probe, is frequently utilized in research to visualize real-time cGMP signaling. With its advantages in investigating the effects of drugs that alter cGMP levels and its role in the progression of diseases such as heart failure and hypertension, this probe offers significant value in scientific research. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 580Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 580Q (free acid). Mole weight: 1135.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-590
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-590 is a high-performance fluorescent marker widely employed in biomedical research to investigate complex cGMP signaling pathways. This exceptionally stable product binds uniquely to cGMP, yielding accurate measurements of intracellular cGMP concentrations and providing valuable insight into its subcellular localization. Consequently, this state-of-the-art technology enables researchers to more thoroughly investigate diseases like hypertension and heart failure. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 590. Grades: ≥ 95% by HPLC. Molecular formula: C53H62N9O11P (free acid). Mole weight: 1032.10 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-594
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-594 is a fluorescent probe widely employed for the visualization of cyclic guanosine monophosphate (cGMP) signaling pathways in cells and tissues. This compound aids in studying the role of cGMP in various biological processes and diseases, including cardiovascular disorders, neuronal signaling and smooth muscle relaxation. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 594, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 594 (free acid). Mole weight: 1246.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-612Q
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-612Q, a fluorescent probe, designed to assist biomedical research in investigating guanylyl cyclase enzyme activity and cGMP-related signaling pathways, as well as studying the pathogenesis of cardiovascular diseases and cancer. The intricacies of this product are profound whilst remaining highly practical, offering a truly unique insight into its potential. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 612Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H24N7O7P - ATTO 612Q (free acid). Mole weight: 1131.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-620
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-620 is a fluorescent dye used to label proteins and peptides. It is commonly used in the biomedical industry to study protein function and localization, as well as in drug discovery to identify potential targets and inhibitors. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 620, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 620 (free acid). Mole weight: 952.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-633
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-633, a fluorescent dye with high sensitivity and specificity, plays a significant role in biomedical research. It is widely used to label and trace intracellular signaling pathways which are linked to cyclic guanosine monophosphate (cGMP). This dye finds profound applications in pulmonary hypertension, erectile dysfunction, and other cardiovascular diseases. It offers an exceptional investigative tool to explore the signaling pathways associated with these ailments. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 633, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 633 (free acid). Mole weight: 992.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-647N
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-647N is a fluorescent probe used for imaging guanylyl cyclase and monitoring cGMP signaling pathways in biological systems. This product can also be utilized in the diagnosis and treatment of disorders related to the activation or inhibition of guanylyl cyclase and cGMP. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 647N, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 647N (free acid). Mole weight: 1086.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-655
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-655, a fluorescent probe that selectively interacts with cyclic GMP, offers a unique opportunity to gain insights into the spatiotemporal regulation of this crucial second messenger in living cells. By illuminating the intricacies of cyclic GMP signaling, this probe promises to unlock the secrets of a wide range of diseases, from cardiovascular disorders to cancer. Witness the power of precision science with this cutting-edge technology. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 655, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 655 (free acid). Mole weight: 968.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-665
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-665 is a fluorescent-labeled nucleotide used in biomedicine to study guanosine cyclic monophosphate (cGMP)-related signaling pathways. It has been used in studies looking at nitric oxide (NO) signaling and the cyclic GMP-protein kinase G (PKG) pathway, which are involved in regulating smooth muscle relaxation. Additionally, it has potential therapeutic applications in treating cardiovascular diseases and pulmonary hypertension. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 665. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 665 (free acid). Mole weight: 1063.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-680
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-680 is a fluorescent labeling molecule used in the biomedical industry for research purposes. It can be used to visualize and track intracellular signaling processes involving cGMP in various cell types, as well as for studying cardiovascular diseases and vascular dysfunction related to nitric oxide (NO) signaling. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 680, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 680 (free acid). Mole weight: 966.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-700
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-700, a fluorescent probe widely used in molecular and cellular biology applications, offers remarkable capabilities in visualizing and monitoring cGMP-mediated signaling pathways in live cells and tissues. With its highly sensitive and specific cGMP detection, it is an invaluable tool for investigating an array of diseases linked with dysfunctional cGMP signaling, such as cardiovascular diseases and erectile dysfunction. Utilizing this state-of-the-art technology yields infinite possibilities for expanding our knowledge of the intricacies of cellular communication and signaling. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 700, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 700 (free acid). Mole weight: 1006.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-740
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-740, a fluorescent probe, is a valuable tool in biomedical research for investigating the function of guanylyl cyclases and soluble guanylate cyclases. Notably, this versatile probe can be used to study the mechanisms underlying cardiovascular diseases and neuronal disorders, thereby offering the potential for significant scientific breakthroughs and medical advancements. Its reliability and efficacy make it a highly sought-after compound for researchers across diverse fields. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 740, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 740 (free acid). Mole weight: 908.39 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-MB2
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-MB2 is a fluorescent probe used in biomedicine to detect cGMP, an important signaling molecule involved in numerous cellular processes. This probe can be used in various applications including in vitro assays, imaging techniques, and drug discovery research related to cGMP-dependent pathways such as cardiovascular diseases and erectile dysfunction. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO-MB2, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C35H45N10O8PS (free acid). Mole weight: 796.83 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho101
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho101, a fluorescent probe extensively used in the biomedical field to scrutinize intracellular signaling of cGMP, is a highly versatile research tool. Delve into drug effects on cGMP signaling pathways while visualizing cGMP's distribution within cells. Moreover, use this probe to diagnose and treat cGMP-related disorders like hypertension and cardiovascular diseases. Embrace the brilliance of this probe to explore the depths of biochemical science. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO Rho101, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C53H63N10O10P (free acid). Mole weight: 1030.45 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho11
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho11 is an indispensable fluorescent probe of significant value in biomedical research for the efficient imaging of cGMP signaling pathways. Its comprehensive functionality further extends to aiding in the effective visualization of cGMP activity across diverse cell types, including neurons and smooth muscle cells. Numerous studies have showcased the presence of cGMP signaling in blood pressure regulation, platelet aggregation, and smooth muscle relaxation, under the influence of nitric oxide. Moreover, cGMP levels can be efficiently monitored by this probe, in sync with the effects of phosphodiesterase inhibitors. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO Rho11, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C51H63N10O10P (free acid). Mole weight: 1006.44 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho12
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho12, a fluorescent nucleotide analog, is a versatile and indispensable tool utilized in biomedical research for the monitoring of nitric oxide signaling and cGMP. Its exceptional ability to act as a molecular probe in investigating spatiotemporal dynamics of cGMP signals and their correlation with physiological and pathological processes such as vasodilation, neurotransmission, and various cancers has been a game-changer in the scientific community. This product is essential for any researcher looking to make groundbreaking discoveries and uncover the secrets of these vital signaling pathways. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO Rho12, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C57H75N10O10P (free acid). Mole weight: 1090.54 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho13
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho13 is a fluorescent probe widely used in the biomedical industry. It exhibiting remarkable specificity for detecting guanosine cyclic monophosphate (cGMP). This probe enables researchers to monitor cGMP levels in various biological processes is aiding in the study of signal transduction pathways and the development of potential researchs for diseases related to cGMP, such as cardiovascular disorders and certain types of cancer. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO Rho13, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C57H71N10O10P (free acid). Mole weight: 1086.51 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho14
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho14 is a powerful fluorescent probe widely utilized in the biomedical industry. This compound plays a crucial role in studying cellular signaling pathways, particularly those involving cGMP. It enables visualize cGMP dynamics and monitor the effects of drugs or diseases on its regulation. With its exceptional fluorescence properties is aTTO-Rho14 facilitates accurate and efficient analysis, contributing to developments in drug discovery and disease understanding. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO Rho14, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C57H67Cl4N10O10P (free acid). Mole weight: 1222.35 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho6G
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Rho6G is a vital tool used in biomedical research to study cellular signaling pathways specifically designed to detect and visualize the presence and activity of the signaling molecule cyclic guanosine monophosphate (cGMP) in live cells. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO Rho6G, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H59N10O10P (free acid). Mole weight: 954.42 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - ATTO-Thio12
8-[(6-Amino)hexyl]-amino-cGMP, a cyclic nucleotide analog, serves as a vital tool in biomedical research to investigate the part played by cyclic nucleotides in cell signaling. It additionally holds potential in studying modulation of intracellular pathways that contribute to the onset of cardiovascular ailments, such as hypertension and heart failure. To help visualize this versatile compound in live cells, ATTO-Thio12, a prominent fluorescent label, can be employed. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO Thio12. Grades: ≥ 95% by HPLC. Molecular formula: C45H55N10O9PS (free acid). Mole weight: 943.02 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP - Biotin
8-[(6-Amino)hexyl]-amino-cGMP - Biotin is a distinctive compound widely employed in the biomedical field, facilitating the investigation of cyclic guanosine monophosphate (cGMP) signaling. Augmented by the incorporation of biotin, this remarkable substance boasts remarkable efficacy in affording researchers with an elevated precision in detection and visualization techniques. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate - Biotin, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C26H40N9O9PS (free acid). Mole weight: 685.69 (free acid).
8-[(6-Amino)hexyl]-amino-cGMP (Biotin)
Biotin-labeled Nucleotides are used for non-fluorescent labeling of nucleic acids in purification and detection applications. Group: Biochemicals. Alternative Names: 8-[(6-Amino)hexyl]-amino-guanosine-3,5-cyclic Monophosphate (Biotin), Triethylammonium Salt. Grades: Highly Purified. Pack Sizes: 50ul. US Biological Life Sciences.
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8-[(6-Amino)hexyl]-amino-cGMP - Cy3
8-[(6-Amino)hexyl]-amino-cGMP - Cy3, a fluorescent cGMP analog, is a potent visualizing tool of cGMP signaling pathways for live-cell imaging. Demonstrating remarkable sensitivity as a reporter of cGMP levels, this compound has been pivotal in exploring the intricacies of hypertension and heart failure as well as functioning as a multifaceted investigative substrate in a plethora of diseases. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H62N9O14PS2 (free acid). Mole weight: 1072.15 (free acid).
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