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CGP 52411 CGP 52411, also called DAPH, inhibits and reverses the formation of Aβ42 fibers (β-sheet content of aggregated β-amyloid (1-42): IC50 = 4.5 μM) in neurons associated with Alzheimer's disease. And it is also a selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro). Uses: Anti-alzheimer agents; amyloid-β inhibitor. Synonyms: CGP 52411; CGP52411; CGP-52411; 5,6-dianilinoisoindole-1,3-dione; 406-050-3; Z13D008FZ2; 4,5-dianilinophthalimide; DAPH; Cgp 52411; 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione; 145915-58-8; Cgp-52411; UNII-Z13D008FZ2; CHEMBL268868; 5,6-dianilino-1h-isoindole-1,3(2h)-dione; CHEBI:53110; Z13D008FZ2; AC1Q6JME; DAPH-1; SCHEMBL11017; 4,5-Bis(anilino)phthalimide; D3943_SIGMA; 4,5-bis-(anilino)phthalimide; AC1L1C19; ZINC6094; DTXSID4040393; CTK8D4606; AAALVYBICLMAMA-UHFFFAOYSA-N; BCPP000288; HMS3260P13; 5,6-dianilinoisoindole-1,3-dione; Tox21_500236; ABP000886; AR-1G6110; BDBM50040929; MFCD00236442; AKOS024457581; BCP9000511; CCG-221540; LP00236; CGP 52411/CGP52411; NCGC00093700-01; NCGC00093700-02; NCGC00093700-03; NCGC00093700-04; NCGC00093700-05; NCGC00260921-01; AK393267; HE062397; HE312151; 5,6-Bis-phenylamino-isoindole-1,3-dione; 5,6-Bis(phenylamino)isoindoline-1,3-dione; J587.895K; 1H-Isoindole-1,3(2H)-dione, 5,6-bis(phenylamino)-; BRD-K13087974-001-01-7; CGP 52411|DAPH|5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione. CAS No. 145915-58-8. Molecular formula: C20H15N3O2. Mole weight: 329.35. BOC Sciences 10
CGP 52411 CGP 52411. Group: Biochemicals. Grades: Purified. CAS No. 145915-58-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
CGP52411 CGP52411, also known as DAPH, is a selective inhibitor of the epidermal growth factor receptor (EGFR). It is also inhibits and reverses the formation of Aβ42 fibers associated with Alzheimer's disease. It may offer therapeutic agents for the treatment of hyperproliferative diseases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CGP52411; CGP 52411; CGP-52411; DAPH. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 145915-58-8. Molecular formula: C20H15N3O2. Mole weight: 329.36. Purity: >98%. IUPACName: 5,6-bis(phenylamino)isoindoline-1,3-dione. Canonical SMILES: O=C1NC(C2=CC(NC3=CC=CC=C3)=C(C=C21)NC4=CC=CC=C4)=O. Product ID: ACM145915588-1. Alfa Chemistry — ISO 9001:2015 Certified. Categories: 4,5-dianilinophthalimide. Alfa Chemistry.
4,5-Dianilinophthalimide 4,5-Dianilinophthalimide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DAPH;CGP 52411;5,6-BIS(PHENYLAMINO)-1H-ISOINDOLE-1,3(2H)-DIONE;4,5-DIANILINOPHTHALIMIDE;4,5-DIANILINOPHTHALIMIDE[DAPH];1H-Isoindole-1,3(2H)-dione, 4,5-bis(phenylamino)-;4,5-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione;Daph1. Product Category: Heterocyclic Organic Compound. CAS No. 157168-02-0. Molecular formula: C20H15N3O2. Mole weight: 329.35. Purity: 0.96. IUPACName: 4,5-dianilinoisoindole-1,3-dione. Canonical SMILES: C1=CC=C(C=C1)NC2=C(C3=C(C=C2)C(=O)NC3=O)NC4=CC=CC=C4. Density: 1.374g/cm³. Product ID: ACM157168020. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5

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